Eriksson Kare, Wiklund Leif
Department of Occupational and Environmental Medicine, University Hospital of Northern Sweden, SE-901 85 Umea, Sweden.
J Environ Monit. 2004 Jun;6(6):563-8. doi: 10.1039/b401666c. Epub 2004 Apr 7.
The dermal exposure to the suspected allergenic monoterpenes [small alpha]-pinene, [small beta]-pinene and capital Delta-carene was assessed with a patch sampling technique. The patch used was made of activated charcoal sandwiched between two layers of cotton cloth. Patches were fastened at 12 different spots on a sampling overall and at the front of a cap to estimate the potential exposure of the body. Fastening two patches on a cotton glove, one patch representing the dorsal side and one patch representing the palm of the hand respectively, assessed the exposure on the hands. Sampling was carried out during collecting of pine and spruce boards in sawmills and during sawing of pine wood pieces in joinery shops respectively. The potential dermal exposure of the total body was 29.0-1 890 mg h(-1) with a geometric mean (GM) of 238 mg h(-1) during sawing. During collecting the GM was estimated to 100 mg h(-1) with a range of 12.2-959 mg h(-1). The hands had a mean exposure of 9.24 mg h(-1) during sawing and 3.25 mg h(-1) during collecting respectively. The good correlation between the mass of contamination on the individual body parts and the potential body exposure indicates that sampling can be performed on one body part to give a good estimation of the potential body exposure. Monoterpenes were detected at patches fastened underneath the protective clothing indicating a contamination of the skin of the worker. The patch used may overestimate the dermal exposure.
采用贴片采样技术评估了皮肤对疑似变应原性单萜类物质α-蒎烯、β-蒎烯和Δ(3)-蒈烯的暴露情况。所用贴片由夹在两层棉布之间的活性炭制成。在采样工作服和帽子前部的12个不同部位固定贴片,以估计身体的潜在暴露量。在棉手套上固定两片贴片,一片代表手背,一片代表手掌,以此评估手部的暴露情况。采样分别在锯木厂收集松木和云杉木板期间以及细木工车间锯切松木片期间进行。锯切过程中,全身的潜在皮肤暴露量为29.0 - 1890 mg h⁻¹,几何平均值(GM)为238 mg h⁻¹。收集期间,GM估计为100 mg h⁻¹,范围为12.2 - 959 mg h⁻¹。手部在锯切期间的平均暴露量分别为9.24 mg h⁻¹,收集期间为3.25 mg h⁻¹。个体身体部位的污染量与潜在身体暴露量之间的良好相关性表明,可以在一个身体部位进行采样,以很好地估计潜在身体暴露量。在防护服下面固定的贴片上检测到了单萜类物质,这表明工人的皮肤受到了污染。所用贴片可能高估了皮肤暴露量。