Binder Devin K, Smith Justin S, Barbaro Nicholas M
Department of Neurological Surgery, University of California, San Francisco, California 94143-0112, USA.
Neurosurg Focus. 2004 May 15;16(5):E11. doi: 10.3171/foc.2004.16.5.12.
The authors report on the treatment of primary brachial plexus tumors in 25 patients at the University of California, San Francisco. They compare their findings with those obtained in similar series.
The authors reviewed the electronic and medical records, radiological images, operative reports, and pathological findings in 25 consecutive cases of primary brachial plexus tumors. Cases of metastatic lesions or adjacent neoplasms extending into and involving the brachial plexus were excluded. At presentation patients ranged in age from 19 to 71 years (mean 47-15 years), and neurofibromatosis was present in eight patients (32%). Presenting signs and symptoms included palpable mass (60%), numbness/paresthesias (44%), radiating pain (44%), local pain (16%), and weakness (12%). Duration of symptoms ranged from 2 months to 10 years. Neuroimaging revealed lesions ranging widely in size (volume approximately 1 to 100 ml). Pathological diagnoses included schwannoma (15 [60%]), neurofibroma (five [20%]), malignant peripheral nerve sheath tumor (four [16%]), and desmoid tumor (one [4%]).
Primary tumors arising in the brachial plexus are rare. Careful workup, surgical technique, and attention to pathological diagnosis optimize management.
作者报告了加利福尼亚大学旧金山分校对25例原发性臂丛神经肿瘤的治疗情况。他们将自己的研究结果与类似系列研究的结果进行了比较。
作者回顾了25例连续的原发性臂丛神经肿瘤病例的电子病历、医疗记录、放射影像、手术报告和病理检查结果。排除转移性病变或延伸至并累及臂丛神经的相邻肿瘤病例。就诊时患者年龄在19岁至71岁之间(平均47.15岁),8例患者(32%)患有神经纤维瘤病。主要体征和症状包括可触及肿块(60%)、麻木/感觉异常(44%)、放射性疼痛(44%)、局部疼痛(16%)和无力(12%)。症状持续时间从2个月到10年不等。神经影像学显示病变大小差异很大(体积约1至100毫升)。病理诊断包括神经鞘瘤(15例[60%])、神经纤维瘤(5例[20%])、恶性周围神经鞘膜瘤(4例[16%])和硬纤维瘤(1例[4%])。
起源于臂丛神经的原发性肿瘤很少见。仔细的检查、手术技术以及对病理诊断的关注可优化治疗管理。