Tanabe Paula, Steinmann Rebecca, Anderson Jill, Johnson Deborah, Metcalf Sue, Ring-Hurn Eileen
Institute for Health Services Research and Policy Studies and Division of Emergency Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Acad Emerg Med. 2004 Jun;11(6):699-702.
To compare pain and discomfort ratings of female patients undergoing urethral catheterization randomized to topical application of plain lubricant versus lidocaine gel prior to the procedure.
This was a prospective, randomized, double-blind study involving female patients requiring urethral catheterization at an urban university-based academic emergency department. A staff nurse blinded to the lubricant type injected 5 mL of sterile surgical lubricant or 2% lidocaine gel into the urinary meatus. After 1 minute, an 8-F (for specimen collection) or a 16-F (for continuous collection) catheter was inserted into the urethra. Each patient rated the pain of the procedure on a validated 0- to 100-mm visual analog scale. The Mann-Whitney U test was used to analyze associations between pain ratings, lubricant type, and catheter size. Logistic regression was used to identify the contribution of lubricant type, catheter size, age category, difficulty of insertion, preprocedural pain, and diagnosis of urinary tract infection to procedural pain rating.
One hundred women were randomized to plain lubricant (n = 50) or lidocaine (n = 50). The overall mean ( +/- SD) pain score was 23.5 +/- 27.2 mm. No significant differences in pain ratings were found based on catheter size or lubricant type. Younger women, aged 18-59 years, experienced higher pain ratings than women aged 60-101 (mean pain difference 14.4 mm; 95% CI = 4.3 to 24.5; p < 0.006). Multiple logistic regression identified preprocedural pain as the only predictor of higher pain rating after catheterization (OR 1.02; 95% CI = 1.002 to 1.039, p = 0.03).
Catheter size and lubricant type did not affect the severity of pain after urethral catheterization in women.
比较在尿道插管术前随机接受普通润滑剂局部应用与利多卡因凝胶局部应用的女性患者的疼痛和不适评分。
这是一项前瞻性、随机、双盲研究,涉及在一所城市大学附属医院急诊科需要进行尿道插管的女性患者。一名对润滑剂类型不知情的护士将5毫升无菌手术润滑剂或2%利多卡因凝胶注入尿道口。1分钟后,将一根8F(用于标本采集)或16F(用于持续采集)的导尿管插入尿道。每位患者使用经过验证的0至100毫米视觉模拟量表对操作过程中的疼痛进行评分。采用曼-惠特尼U检验分析疼痛评分、润滑剂类型和导尿管尺寸之间的关联。使用逻辑回归来确定润滑剂类型、导尿管尺寸、年龄类别、插入难度、术前疼痛以及尿路感染诊断对操作疼痛评分的影响。
100名女性被随机分为接受普通润滑剂组(n = 50)或利多卡因组(n = 50)。总体平均(±标准差)疼痛评分为23.5±27.2毫米。基于导尿管尺寸或润滑剂类型,未发现疼痛评分有显著差异。18至59岁的年轻女性比60至101岁的女性经历了更高的疼痛评分(平均疼痛差异14.4毫米;95%置信区间 = 4.3至24.5;p < 0.006)。多元逻辑回归确定术前疼痛是插管后疼痛评分较高的唯一预测因素(比值比1.02;95%置信区间 = 1.002至1.039,p = 0.03)。
导尿管尺寸和润滑剂类型不影响女性尿道插管术后的疼痛严重程度。