Won Je Hwan, Kim Byung Moon, Kim Chul-Ho, Park Sang Woo, Kim Man Deuk
Department of Diagnostic Radiology, Ajou University Hospital, College of Medicine, Suwon, Korea.
J Vasc Interv Radiol. 2004 Jun;15(6):595-600. doi: 10.1097/01.rvi.0000127899.31047.0e.
To evaluate the efficacy of percutaneous image-guided sclerotherapy of lymphangiomas with use of acetic acid.
Twelve patients with lymphangiomas were treated with acetic acid as the sclerosant. There were eight male patients and four female patients, ranging in age from 1 to 29 years (mean, 11 years). The lymphangiomas were located at the neck (n = 5), upper extremity (n = 3), axilla (n = 1), cervicomediastinum (n = 1), anterior chest wall (n = 1), and retroperitoneum (n = 1). Two patients had recurrent lymphangiomas after surgery and two patients had undergone failed sclerotherapy with another sclerosant. The acetic acid used as the sclerosant was 40%-50% in concentration, and the amounts used ranged from 2 mL to 70 mL (mean, 11.3 mL), which was equivalent to 4.6%-50% (mean, 30.6%) of the aspirated lymphatics. All procedures were performed under ultrasonographic and fluoroscopic guidance. The sclerosant was removed after sclerotherapy. All patients except one underwent one treatment session.
Complete resolution of the lymphangioma was achieved in eight patients (66.7%), good resolution (>50% reduction) was achieved in three (25.0%), and poor resolution (<50% reduction) was seen in one (8.3%). Complications encountered included pneumonitis adjacent to the lymphangioma (n = 1), pain (n = 2), hematuria (n = 1), and tingling sensation in the forearm (n = 1).
Percutaneous sclerotherapy of the lymphangiomas with use of acetic acid is an effective method without serious complications.