Molitch H I, Unger E C, Witte C L, vanSonnenberg E
Department of Radiology, University of Arizona, Tucson 85724.
Radiology. 1995 Feb;194(2):343-7. doi: 10.1148/radiology.194.2.7529933.
The authors report their experience with percutaneous image-guided sclerotherapy for treatment of unresectable lymphangiomas.
Five patients with unresectable lymphangiomas of the pelvis (n = 2), neck (n = 1), abdomen (n = 1), or leg (n = 1) were treated at two medical centers with sclerotherapy, with use of doxycycline as the sclerosant. Computed tomography was used to guide the procedures, with supplemental lymphoscintigraphy, ultrasound, and magnetic resonance imaging used as needed.
Symptomatic relief of lymphedema, lymphorrhea, or a decrease in size of lymphatic pools was achieved, to varying degrees, in the five patients. Follow-up is ongoing, and further sclerotherapy may be indicated as the clinical course dictates.
Percutaneous sclerotherapy with doxycycline is safe and appears effective for palliative treatment of unresectable lymphangiomas on the basis of our initial clinical experience.
作者报告经皮影像引导下硬化治疗不可切除淋巴管瘤的经验。
在两个医疗中心对5例不可切除的盆腔（n = 2）、颈部（n = 1）、腹部（n = 1）或腿部（n = 1）淋巴管瘤患者进行硬化治疗，使用强力霉素作为硬化剂。采用计算机断层扫描引导操作，必要时辅以淋巴闪烁显像、超声和磁共振成像。
5例患者均不同程度地实现了淋巴水肿、淋巴漏症状缓解或淋巴池大小减小。随访正在进行，根据临床病程可能需要进一步进行硬化治疗。
根据我们最初的临床经验，强力霉素经皮硬化治疗对于不可切除淋巴管瘤的姑息治疗是安全且有效的。
