Suppr超能文献

脑静脉血栓形成

Cerebral venous thrombosis.

作者信息

Crassard Isabelle, Bousser Marie-Germaine

机构信息

Department of Neurology, Hôpital Lariboisière, Paris, France.

出版信息

J Neuroophthalmol. 2004 Jun;24(2):156-63. doi: 10.1097/00041327-200406000-00011.

Abstract

Cerebral venous thrombosis is an infrequent condition characterized by extreme variability in its clinical presentation and mode of onset. The combination of magnetic resonance imaging and magnetic resonance angiography is currently the best method for diagnosis. The proportion of cases of unknown etiology remains high. The prognosis, although better than previously thought, remains unpredictable. Treatment, which should be started as soon as the diagnosis is established, consists of reversing the underlying cause when known, control of seizures and intracranial hypertension, and the use of antithrombotics. Heparin should be the first-line antithrombotic agent. Recent studies have confirmed its safety even in patients with hemorrhagic parenchymal lesions. Local thrombolysis is indicated in the very rare cases that deteriorate despite adequate anticoagulation. Cerebrospinal fluid diversion or optic nerve fenestration is used for vision-threatening papilledema when intracranial pressure control is difficult.

摘要

脑静脉血栓形成是一种罕见疾病,其临床表现和发病方式具有极大的变异性。磁共振成像和磁共振血管造影相结合目前是最佳诊断方法。病因不明的病例比例仍然很高。尽管预后比以前认为的要好,但仍然不可预测。一旦确诊就应开始治疗,包括在已知病因时逆转潜在病因、控制癫痫发作和颅内高压以及使用抗栓药物。肝素应作为一线抗栓药物。最近的研究已证实其安全性,即使在有出血性实质病变的患者中也是如此。在极少数尽管充分抗凝仍恶化的病例中,可进行局部溶栓治疗。当颅内压难以控制时,脑脊液分流或视神经开窗术用于治疗威胁视力的视乳头水肿。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验