Zuber Mathieu, Meder Jean-François
Service de Neurologie et Unité Neurovasculaire, Hôpital Sainte-Anne, Université Paris-Descartes, 75014 Paris.
Rev Prat. 2006 Apr 30;56(8):829-37.
Cerebral venous thrombosis is a rare and life threatening condition that should be considered in all individual with unusual and intractable headache. Young adults and children are typically affected and the superior sagittal sinus is most often concerned by thrombosis. MRI is the most sensitive examination technique and is now required for early diagnosis, leading to an improved prognosis. One or several prothrombotic risk factors are identified in most patients but about 20% of cerebral venous thrombosis have no cause identified. Anticoagulation is started as soon as the diagnosis is considered, even in the presence of hemorrhagic infarcts, and rapidly improves the condition in most patients. In situ thrombolysis is exceptionally delivered.
脑静脉血栓形成是一种罕见且危及生命的疾病,所有患有异常顽固性头痛的个体均应考虑此病。年轻人和儿童是典型的受累人群,上矢状窦最常发生血栓形成。磁共振成像(MRI)是最敏感的检查技术,现在是早期诊断所必需的,从而改善预后。大多数患者可识别出一种或几种血栓形成前危险因素,但约20%的脑静脉血栓形成病因不明。一旦考虑诊断,即使存在出血性梗死,也应立即开始抗凝治疗,大多数患者的病情会迅速改善。原位溶栓极为罕见。