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视觉和模态非特异性脑区的语言处理:选择性注意期间的正电子发射断层扫描记录

Linguistic processing in visual and modality-nonspecific brain areas: PET recordings during selective attention.

作者信息

Vorobyev Victor A, Alho Kimmo, Medvedev Svyatoslav V, Pakhomov Sergey V, Roudas Marina S, Rutkovskaya Julia M, Tervaniemi Mari, Van Zuijen Titia L, Näätänen Risto

机构信息

Institute of the Human Brain, Russian Academy of Sciences, St. Petersburg, Russia.

出版信息

Brain Res Cogn Brain Res. 2004 Jul;20(2):309-22. doi: 10.1016/j.cogbrainres.2004.03.011.

Abstract

Positron emission tomography (PET) was used to investigate the neural basis of selective processing of linguistic material during concurrent presentation of multiple stimulus streams ("cocktail-party effect"). Fifteen healthy right-handed adult males were to attend to one of three simultaneously presented messages: one presented visually, one to the left ear, and one to the right ear. During the control condition, subjects attended to visually presented consonant letter strings and ignored auditory messages. This paper reports the modality-nonspecific language processing and visual word-form processing, whereas the auditory attention effects have been reported elsewhere [Cogn. Brain Res. 17 (2003) 201]. The left-hemisphere areas activated by both the selective processing of text and speech were as follows: the inferior prefrontal (Brodmann's area, BA 45, 47), anterior temporal (BA 38), posterior insular (BA 13), inferior (BA 20) and middle temporal (BA 21), occipital (BA 18/30) cortices, the caudate nucleus, and the amygdala. In addition, bilateral activations were observed in the medial occipito-temporal cortex and the cerebellum. Decreases of activation during both text and speech processing were found in the parietal (BA 7, 40), frontal (BA 6, 8, 44) and occipito-temporal (BA 37) regions of the right hemisphere. Furthermore, the present data suggest that the left occipito-temporal cortex (BA 18, 20, 37, 21) can be subdivided into three functionally distinct regions in the posterior-anterior direction on the basis of their activation during attentive processing of sublexical orthography, visual word form, and supramodal higher-level aspects of language.

摘要

正电子发射断层扫描(PET)被用于研究在多个刺激流同时呈现期间(“鸡尾酒会效应”)语言材料选择性加工的神经基础。15名健康的右利手成年男性需要关注同时呈现的三条信息中的一条:一条视觉呈现,一条左耳呈现,一条右耳呈现。在对照条件下,受试者关注视觉呈现的辅音字母串并忽略听觉信息。本文报告了模态非特异性语言加工和视觉词形加工,而听觉注意效应已在其他地方报道过[《认知脑研究》17(2003)201]。由文本和语音的选择性加工激活的左半球区域如下:额下回(布罗德曼区,BA 45、47)、颞前叶(BA 38)、岛叶后部(BA 13)、颞下回(BA 20)和颞中回(BA 21)、枕叶(BA 18/30)皮质、尾状核和杏仁核。此外,在内侧枕颞叶皮质和小脑中观察到双侧激活。在右半球的顶叶(BA 7、40)、额叶(BA 6、8、44)和枕颞叶(BA 37)区域发现了文本和语音加工期间激活的减少。此外,目前的数据表明,基于在亚词汇正字法、视觉词形和语言的超模态高级方面的注意加工期间的激活情况,左枕颞叶皮质(BA 18、20、37、21)可以在前后方向上细分为三个功能不同的区域。

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