Flórez Angeles, Cruces Manuel
Department of Dermatology, Complejo Hospitalario de Pontevedra, C/Loureiro Crespo 2, Pontevedra 36001, Spain.
Int J Dermatol. 2004 Jun;43(6):405-7. doi: 10.1111/j.1365-4632.2004.02004.x.
Melanoma incidence has increased dramatically over the last decades in most industrial countries, mainly as a result of the large numbers of early melanomas being diagnosed. Simultaneously, a lack of commensurate change in mortality has been reported, raising the possibility that skin melanoma may have modified its aggressiveness as a result of the increased diagnosis of biologically benign lesions. The main data and controversies arising from the melanoma epidemic are reviewed.
在过去几十年里,大多数工业化国家的黑色素瘤发病率急剧上升,主要原因是大量早期黑色素瘤得到诊断。与此同时,有报告称死亡率没有相应变化,这增加了一种可能性,即由于对生物学上良性病变的诊断增加,皮肤黑色素瘤的侵袭性可能已经改变。本文综述了黑色素瘤流行所产生的主要数据和争议。