Nitzan Daniel, Yahalom Ran, Taicher Shlomo
Chaim Sheba Medical Center, Tel Hashomer.
Harefuah. 2004 May;143(5):335-8, 391.
Silicone is considered a biocompatible material, and therefore has many applications in medicine. It can be used in a liquid form for subcutaneous injection, in gel form for implants, and in a solid state for prostheses, hemodialysis tubing, etc. The use of injectable liquid silicone for tissue augmentation is widespread, but there are many reports of side effects, some severe and debilitating such as the granulomatous reaction. We report on a patient with an upper lip swelling, who denied having been subjected to any type of lip augmentation. An incisional biopsy was taken, and the pathologist reported an atypical lyphomatous tumor. The patient was informed that a wide excision of the lip was necessary, and then she confessed she underwent silicone injections in the past. This is a case of a granulomatous reaction after silicone injection in the lip. The article also reviews the literature on the subject.
硅酮被认为是一种生物相容性材料，因此在医学上有许多应用。它可以以液体形式用于皮下注射，以凝胶形式用于植入物，以固态形式用于假体、血液透析管等。可注射液体硅酮用于组织填充的情况很普遍，但有许多关于副作用的报道，有些副作用严重且使人衰弱，如肉芽肿反应。我们报告了一名上唇肿胀的患者，她否认曾接受过任何类型的唇部填充。进行了切开活检，病理学家报告为非典型淋巴瘤样肿瘤。告知患者有必要对唇部进行广泛切除，然后她承认过去曾接受过硅酮注射。这是一例唇部注射硅酮后发生肉芽肿反应的病例。本文还综述了关于该主题的文献。
