Edelstein Shimon, Edoute Yeuda
Department of Internal Medicine C, Rambam Medical Center, Haifa, Israel.
Harefuah. 2004 May;143(5):364-7, 390.
Q fever is a zoonotic disease caused by Coxiella burnetii--an obligate, gram negative, intracellular bacteria. The term Q (Query) was first used because at the time the disease was named its etiology was unknown. Q fever is divided into acute and chronic infections characterized by different evolution, serological profiles and treatment. Pericarditis, as a manifestation of Q fever is rare and difficult to diagnose. This is due to the following: firstly, the clinical presentation of acute Q fever is pleomorphic, nonspecific and self limited, and secondly, the diagnosis relies on the physician's interest and the presence of a reliable diagnostic laboratory. The objective of that review is to increase the physician's awareness of the clinical presentation of Q fever, to discuss the importance of the diagnosis and laboratory tests and to guide the physician as to when to provide treatment and the relevant patient population to be treated.
Q热是一种由伯氏考克斯体引起的人畜共患病,伯氏考克斯体是一种专性、革兰氏阴性、细胞内细菌。术语Q(疑问)最初被使用是因为在该疾病被命名时其病因尚不清楚。Q热分为急性和慢性感染,其特征在于不同的病程发展、血清学特征和治疗方法。作为Q热表现形式的心包炎很少见且难以诊断。原因如下:首先,急性Q热的临床表现具有多形性、非特异性且为自限性;其次,诊断依赖于医生的关注以及可靠诊断实验室的存在。该综述的目的是提高医生对Q热临床表现的认识,讨论诊断和实验室检查的重要性,并指导医生何时进行治疗以及针对哪些相关患者群体进行治疗。