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斯洛伐克一起由未巴氏杀菌的牛奶中产生志贺毒素的大肠杆菌O157引起的溶血性尿毒综合征和出血性结肠炎家庭聚集性疫情。

A family outbreak of haemolytic uraemic syndrome and haemorrhagic colitis caused by verocytotoxigenic Escherichia coli O157 from unpasteurised cow's milk in Slovakia.

作者信息

Liptakova A, Siegfried L, Rosocha J, Podracka L, Bogyiova E, Kotulova D

机构信息

Institute of Medical Microbiology, P J Safarik University, Kosice, Slovakia.

出版信息

Clin Microbiol Infect. 2004 Jun;10(6):576-8. doi: 10.1111/j.1469-0691.2004.00900.x.

Abstract

This report describes a family outbreak of verocytotoxigenic Escherichia coli O157 (VTEC) infection, involving nine persons from one extended family, which occurred in eastern Slovakia. Three children suffered from haemolytic uraemic syndrome, two children had bloody diarrhoea, and four adults were asymptomatic carriers. Fourteen sorbitol-non-fermenting E. coli O157 isolates harbouring the vtx2, eae and ehxA genes were obtained. Verocytotoxin 2 activity was demonstrated in all 14 isolates. After epidemiological surveillance, the source of infection was identified as unpasteurised cow's milk.

摘要

本报告描述了斯洛伐克东部发生的一起产志贺毒素大肠杆菌O157(VTEC)感染的家庭聚集性疫情,涉及一个大家庭的9名成员。3名儿童患上溶血尿毒综合征,2名儿童出现血性腹泻,4名成年人是无症状携带者。获得了14株携带vtx2、eae和ehxA基因的不发酵山梨醇大肠杆菌O157分离株。所有14株分离株均检测出志贺毒素2活性。经过流行病学监测,确定感染源为未经巴氏杀菌的牛奶。

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