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[鞍旁副神经节瘤:一例报告]

[Parasellar paraganglioma: a case report].

作者信息

Riopel Céline, Courville Philippe, Fabre Blandine, Callonnec Françoise, Bolognini Benoît, Marie Jean-Paul, Laquerrière Annie

机构信息

Service d'Anatomie Pathologique, Hôpital Charles Nicolle, CHU de Rouen, 1 rue de Germont, 76031 Rouen.

出版信息

Ann Pathol. 2004 Feb;24(1):62-7. doi: 10.1016/s0242-6498(04)93903-x.

Abstract

A 66-Year-old man presented with diplopia, headache and dizziness. Magnetic resonance imaging showed a right intrasphenoidal paracavernous mass. A biopsy was performed by endonasal route in the lesion which appeared to be part of the hypophyseal fossa. Histological examination revealed a highly cellular tumoral proliferation, with a variable architecture, of which chief cells were immunoreactive for neuroendocrine markers and spindle-shaped cells positive for PS 100. Morphological features were consistent with the diagnosis of paraganglioma. Our observation is the first case of this rare tumor reported in the French literature.

摘要

一名66岁男性出现复视、头痛和头晕症状。磁共振成像显示右侧蝶鞍旁海绵窦区有一肿块。通过鼻内途径对病变进行活检,该病变似乎是垂体窝的一部分。组织学检查显示肿瘤细胞高度增殖,结构多样,其中主细胞对神经内分泌标志物呈免疫反应,梭形细胞对PS 100呈阳性。形态学特征符合副神经节瘤的诊断。我们的观察是法国文献中报道的首例这种罕见肿瘤。

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