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胰胃吻合术:胰体尾切除术后的一种新应用。

Pancreaticogastrostomy: a novel application after central pancreatectomy.

作者信息

Goldstein Michael J, Toman Jared, Chabot John A

机构信息

Department of Surgery, New York Presbyterian Hospital, Columbia Campus, New York, NY 10032, USA.

出版信息

J Am Coll Surg. 2004 Jun;198(6):871-6. doi: 10.1016/j.jamcollsurg.2004.02.026.

Abstract

BACKGROUND

Limited middle segment pancreatectomy, or central pancreatectomy, has been described for sparing normal pancreatic tissue during resection of benign neoplasms of the pancreatic neck. Anatomic reconstruction after central pancreatectomy has been reported in other series with creation of a Roux-en-Y loop of jejunum for a mucosa-to-mucosa pancreaticojejunostomy.

STUDY DESIGN

Hospital charts and outpatient records were reviewed for 12 consecutive patients undergoing central pancreatectomy from August 1999 to November 2002.

RESULTS

We performed central pancreatectomy with pancreaticogastrostomy in 12 patients: 5 with serous cystadenomas, 6 with mucinous cystadenomas, and 1 with neuroendocrine tumor. All tumors were located in the body or neck of the pancreas, measuring a mean +/- standard deviation (SD) of 2.5 +/- 1.2 cm. Median postoperative hospital stay was 6.5 days (range 5 to 15 days). There were no intraoperative complications. Perioperative complications included two urinary tract infections and one readmission for acute pancreatitis. There were no pancreatic leaks or fistulas in this series. Two of the 12 patients experienced endocrine insufficiency with elevated glycosylated hemoglobin levels during outpatient followup. None of the 12 patients experienced exocrine insufficiency.

CONCLUSIONS

Central pancreatectomy with pancreaticogastrostomy reconstruction is safe and technically advantageous over Roux-en-Y pancreaticojejunostomy, and should be considered a safe reconstruction technique after central pancreatectomy for benign disease.

摘要

背景

有限中段胰腺切除术,即中央胰腺切除术,已被描述用于在胰腺颈部良性肿瘤切除术中保留正常胰腺组织。在其他系列报道中,中央胰腺切除术后进行了解剖重建,通过创建空肠Roux-en-Y袢进行黏膜对黏膜的胰肠吻合术。

研究设计

回顾了1999年8月至2002年11月期间连续接受中央胰腺切除术的12例患者的医院病历和门诊记录。

结果

我们对12例患者实施了胰胃吻合的中央胰腺切除术:5例为浆液性囊腺瘤,6例为黏液性囊腺瘤,1例为神经内分泌肿瘤。所有肿瘤均位于胰腺体部或颈部,平均直径±标准差(SD)为2.5±1.2 cm。术后中位住院时间为6.5天(范围5至15天)。术中无并发症。围手术期并发症包括2例尿路感染和1例因急性胰腺炎再次入院。本系列中无胰漏或胰瘘发生。12例患者中有2例在门诊随访期间出现内分泌功能不全,糖化血红蛋白水平升高。12例患者均未出现外分泌功能不全。

结论

胰胃吻合重建的中央胰腺切除术安全且在技术上优于Roux-en-Y胰肠吻合术,应被视为中央胰腺切除术后治疗良性疾病的一种安全重建技术。

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