Talbot H, Hutchinson S P, Edbrooke D L, Wrench I, Kohlhardt S R
Department of Surgery, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.
Anaesthesia. 2004 Jul;59(7):664-7. doi: 10.1111/j.1365-2044.2004.03795.x.
Breast surgery can be emotionally distressing and physically painful. Acute pain following surgery is often related mainly to the axillary surgery and is aggravated by arm and shoulder movement. We conducted a prospective double-blind, randomised, placebo-controlled trial to determine the influence of local anaesthetic irrigation of axillary wound drains on postoperative pain during the first 24 h following a modified Patey mastectomy (mastectomy with complete axillary node clearance). The treatment group received bupivacaine irrigation through the axillary wound drain 4-hourly for 24 h postoperatively. Controls received irrigation with normal saline. Morphine via a patient controlled analgesia pump was used for postoperative analgesia. Morphine consumption, visual analogue and verbal rating pain scores were recorded. There were no statistical differences in morphine requirements or pain scores between the two groups, nor were there differences in anti-emetic or supplemental analgesic consumption. Bupivacaine irrigation used in this manner does not appear to offer an effective contribution to postoperative analgesia.
乳房手术可能在情感上令人痛苦,在身体上带来疼痛。术后急性疼痛通常主要与腋窝手术有关,并且会因手臂和肩部的活动而加重。我们进行了一项前瞻性双盲、随机、安慰剂对照试验,以确定在改良的帕蒂乳房切除术(伴有完整腋窝淋巴结清扫的乳房切除术)后24小时内,局部麻醉药冲洗腋窝伤口引流管对术后疼痛的影响。治疗组在术后24小时内每4小时通过腋窝伤口引流管接受布比卡因冲洗。对照组接受生理盐水冲洗。通过患者自控镇痛泵使用吗啡进行术后镇痛。记录吗啡消耗量、视觉模拟评分和语言评分疼痛分数。两组之间在吗啡需求量或疼痛评分方面没有统计学差异,在止吐药或补充镇痛药的消耗量方面也没有差异。以这种方式使用布比卡因冲洗似乎对术后镇痛没有有效作用。