Heckman George A, Hawkins Cynthia, Morris Andrew, Burrows Lori L, Bergeron Catherine
Department of Medicine, Hamilton Health Sciences, Freeport Health Centre, Kitchener, Ontario, Canada.
Emerg Infect Dis. 2004 May;10(5):924-7. doi: 10.3201/eid1005.030711.
Dementia developed in a patient with widespread neurologic manifestations; she died within 5 months. Pathologic findings showed granulomatous inflammation with caseation necrosis, foreign body-type giant cells, and proliferative endarteritis with vascular occlusions. Broad-range polymerase chain reaction identified Mycobacterium neoaurum as the possible pathogen. Central nervous system infection by M. neoaurum may result in rapidly progressive dementia.
一名患有广泛神经系统表现的患者出现了痴呆症状;她在5个月内死亡。病理检查结果显示为肉芽肿性炎症伴干酪样坏死、异物型巨细胞以及伴有血管闭塞的增生性动脉内膜炎。广谱聚合酶链反应鉴定出耻垢分枝杆菌可能为病原体。耻垢分枝杆菌引起的中枢神经系统感染可能导致快速进展性痴呆。