Salvalaggio Paolo R O, Baker Talia B, Koffron Alan J, Fryer Jonathan P, Clark Lori, Superina Riccardo A, Blei Andres T, Abecassis Michael M
Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Transplantation. 2004 Jun 15;77(11):1765-7. doi: 10.1097/01.tp.0000129406.35825.6d.
We investigated whether right lobe (RL) liver donation is associated with a higher incidence or severity of donor complications than left lobe (LL) liver and left lateral segment (LLS) liver donations. We studied 80 living donors: 35 RL liver donors and 45 LL/LLS liver donors. A modification of the Clavien classification was used to grade the severity of complications. RL and LL/LLS liver donations had equivalent blood loss, readmission and reoperation rates, use of blood products, and lengths of stay in the intensive care unit and hospital. RL liver donors underwent longer surgeries and experienced more postoperative pain than LL/LLS liver donors. The overall rate of complications was 33%. There was a higher rate of complications in RL liver donors (51%) than LL/LLS liver donors (20%). When graded by severity, there were more grade 2 complications in RL liver donors than in LL/LLS liver donors. Our report confirms that RL liver donation is associated with higher morbidity than LL/LLS liver donation. When the complications are systematically graded by severity, there is a significant difference in Clavien grade 2 complications in RL liver donors.
我们调查了右叶（RL）肝捐赠相较于左叶（LL）肝和左外叶（LLS）肝捐赠，是否与供体并发症的发生率更高或更严重相关。我们研究了80名活体供体：35名RL肝供体和45名LL/LLS肝供体。采用改良的Clavien分类法对并发症的严重程度进行分级。RL肝捐赠和LL/LLS肝捐赠在失血量、再次入院和再次手术率、血液制品的使用以及重症监护病房和医院的住院时间方面相当。RL肝供体的手术时间比LL/LLS肝供体更长，术后疼痛更明显。总体并发症发生率为33%。RL肝供体的并发症发生率（51%）高于LL/LLS肝供体（20%）。按严重程度分级时，RL肝供体的2级并发症比LL/LLS肝供体更多。我们的报告证实，RL肝捐赠比LL/LLS肝捐赠的发病率更高。当按严重程度对并发症进行系统分级时，RL肝供体的Clavien 2级并发症存在显著差异。
