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右半肝活体肝移植供者的结局:埃及单中心经验。

Outcome of right hepatectomy for living liver donors: a single Egyptian center experience.

机构信息

Gatrointestinal Surgery and Liver Transplantation Unit, Gastroenterology Surgical Center, Mansoura University, Gehan Street, Mansoura, Egypt.

出版信息

J Gastrointest Surg. 2012 Jun;16(6):1181-8. doi: 10.1007/s11605-012-1851-4. Epub 2012 Feb 28.

DOI:10.1007/s11605-012-1851-4
PMID:22370735
Abstract

BACKGROUND

This study aims to evaluate living liver donor outcome after right hepatectomy in a single Egyptian center.

PATIENTS AND METHODS

Between April 2004 and July 2010, 100 living donors underwent right hepatectomy. Their medical records and postoperative follow-up visits were retrospectively revised. Perioperative complications were reported. Postoperative complications were classified according to the five tier version of Clavien system.

RESULTS

There were 71 males and 29 females. The mean age was 27.6 ± 7.4 years. The mean graft weight was 999 ± 167 g and the mean volume percent of the remaining liver was 36.8 ± 8%. The mean ICU and hospital stay were 2.6 ± 2.7 and 12.4 ± 9.1, respectively. A total of 57 complications developed in 38 donors (38%). The commonest complication type was biliary complications. There were 22 grade I, 6 grade II, 15 grade IIIa, 12 grade IIIb, 1 grade IVa, and 1 grade V complications. One donor died due to posttransfusion ARDS on the 30th postoperative day. On follow-up, no donor developed long lasting disability. A donor died in a road traffic accident 1 year after donation.

DISCUSSION AND CONCLUSIONS

Donor right hepatectomy is not an entirely safe procedure. Biliary complications are the commonest early postoperative complications.

摘要

背景

本研究旨在评估单中心埃及的活体肝移植供者右半肝切除术后的结局。

患者与方法

2004 年 4 月至 2010 年 7 月期间,有 100 名活体供者接受了右半肝切除术。回顾性修订了他们的病历和术后随访情况。报告了围手术期并发症。术后并发症根据 Clavien 五级分类系统进行分类。

结果

有 71 名男性和 29 名女性。平均年龄为 27.6±7.4 岁。平均供肝重量为 999±167g,剩余肝脏体积百分比为 36.8±8%。平均 ICU 住院时间和总住院时间分别为 2.6±2.7 和 12.4±9.1 天。38 名供者(38%)共发生 57 种并发症。最常见的并发症类型是胆漏。有 22 例Ⅰ级、6 例Ⅱ级、15 例Ⅲa 级、12 例Ⅲb 级、1 例Ⅳa 级和 1 例Ⅴ级并发症。1 名供者在术后第 30 天因输血后 ARDS 死亡。随访期间,无供者出现长期残疾。1 名供者在捐赠后 1 年死于道路交通意外。

讨论与结论

供者右半肝切除术并非完全安全的手术。胆漏是最常见的早期术后并发症。

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Analysis of surgical and perioperative complications in seventy-five right hepatectomies for living donor liver transplantation.75例活体供肝肝移植右半肝切除术的手术及围手术期并发症分析
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Donor morbidity after living donation for liver transplantation.活体肝移植供体的术后并发症
夹闭-压榨法与超声刀在活体肝移植肝叶切除术中肝实质离断的随机对照研究。
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World J Gastroenterol. 2014 Dec 28;20(48):18061-9. doi: 10.3748/wjg.v20.i48.18061.
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Problem of living liver donation in the absence of deceased liver transplantation program: Mansoura experience.在缺乏尸体肝移植项目的情况下活体肝捐献的问题:曼苏拉经验
World J Gastroenterol. 2014 Oct 7;20(37):13607-14. doi: 10.3748/wjg.v20.i37.13607.
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