结直肠癌患者血浆中磷脂酶A2和血小板活化因子乙酰水解酶活性升高。
Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.
作者信息
Denizot Yves, Truffinet Véronique, Bouvier Stéphane, Gainant Alain, Cubertafond Pierre, Mathonnet Muriel
机构信息
Laboratoire d'immunologie, Faculté de Médecine, UMR CNRS 6101, 2 rue Dr. Marcland, Limoges, France.
出版信息
Mediators Inflamm. 2004 Feb;13(1):53-4. doi: 10.1080/09629350410001664824.
Abstract
This clinical study reports that blood levels of the pro-inflammatory mediator platelet-activating factor (PAF) did not change in colorectal cancer patients. In contrast, plasma levels of two enzymatic activities, one implicated in PAF production (i.e. phospholipase A2) and one in PAF degradation (i.e. PAF acetylhydrolase activity) were significantly elevated.
摘要
这项临床研究报告称，结直肠癌患者体内促炎介质血小板活化因子（PAF）的血液水平没有变化。相比之下，两种酶活性的血浆水平显著升高，一种与PAF产生有关（即磷脂酶A2），另一种与PAF降解有关（即PAF乙酰水解酶活性）。
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