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梗阻性输尿管囊肿——一项持续存在的挑战。

Obstructive ureterocele-an ongoing challenge.

作者信息

Merlini E, Lelli Chiesa P

机构信息

Department of Paediatric Surgery, Maggiore della Carità Hospital, Corso Mazzini 18, Novara, Italy.

出版信息

World J Urol. 2004 Jun;22(2):107-14. doi: 10.1007/s00345-004-0407-y. Epub 2004 Jun 15.

Abstract

Ureterocele is a cystic dilatation of the intravesical ureter that is most commonly observed in females and children, and usually affects the upper moiety of a complete pyeloureteral duplication. According to their position, ureteroceles are divided into intravesical, when the ureterocele is completely contained inside the bladder, and extravesical when part of the cyst extends to the urethra or bladder neck. Most ureteroceles are diagnosed in utero or immediately after birth during an echographic screening of renal malformations. Severe, febrile urinary tract infection is the most common postnatal presentation of ureteroceles, but they may, rarely, prolapse and acutely obstruct the bladder outlet. Once an ureterocele is identified sonographically, a voiding cystourethrogram to detect vesicoureteral reflux (VUR) and a 99m-technetium dimercapto-succinic acid renal scan to evaluate the function of the different portions of the kidney are mandatory. VUR in the lower pole is observed in 50% of cases and in the contralateral kidney in 25%. Simple endoscopic puncture of the ureterocele has recently been advocated as an emergency therapy for infected or obstructing ureteroceles and as an elective therapy for intravesical ureteroceles. The rate of additional surgery after elective endoscopic puncture of an orthotopic ureterocele ranges from 7 to 23%. Treatment of ectopic ureteroceles is more challenging and both endoscopic puncture and upper pole partial nephrectomy frequently require additional surgery at the bladder level. The reoperation rate after endoscopic treatment varies from 48 to 100%. It is 15 to 20% after upper pole partial nephrectomy if VUR was absent before the operation, but is as high as 50-100% when VUR was present. Thus, endoscopic incision is appropriate as an emergency treatment or when dealing with a completely intravesical ureterocele. Upper pole partial nephrectomy is the elective treatment for an ectopic ureterocele without preoperative VUR. In an ectopic ureterocele with VUR, no matter which type of primary therapy has been chosen, a secondary procedure at the bladder level, involving ureterocele removal and reimplantation of the ureter(s), should be anticipated.

摘要

输尿管囊肿是膀胱内输尿管的囊性扩张,最常见于女性和儿童,通常影响完全性肾盂输尿管重复畸形的上半部分。根据其位置,输尿管囊肿分为膀胱内型(输尿管囊肿完全位于膀胱内)和膀胱外型(囊肿部分延伸至尿道或膀胱颈)。大多数输尿管囊肿是在产前超声筛查肾脏畸形时或出生后立即被诊断出来的。严重的发热性尿路感染是输尿管囊肿最常见的产后表现,但它们很少会脱垂并急性阻塞膀胱出口。一旦通过超声检查发现输尿管囊肿,必须进行排尿性膀胱尿道造影以检测膀胱输尿管反流(VUR),并进行99m锝二巯基丁二酸肾扫描以评估肾脏不同部分的功能。50%的病例在下极观察到VUR,25%的病例在对侧肾脏观察到VUR。最近有人主张对感染或阻塞性输尿管囊肿进行简单的内镜下穿刺作为紧急治疗,对膀胱内输尿管囊肿进行选择性治疗。原位输尿管囊肿选择性内镜穿刺后的再次手术率为7%至23%。异位输尿管囊肿的治疗更具挑战性,内镜穿刺和上极部分肾切除术通常都需要在膀胱层面进行额外手术。内镜治疗后的再次手术率在48%至100%之间。如果术前没有VUR,上极部分肾切除术后的再次手术率为15%至20%,但如果术前存在VUR,再次手术率高达50% - 100%。因此,内镜下切开术适合作为紧急治疗或处理完全位于膀胱内的输尿管囊肿时使用。上极部分肾切除术是术前无VUR的异位输尿管囊肿的选择性治疗方法。对于有VUR的异位输尿管囊肿,无论选择哪种主要治疗方法,都应预期在膀胱层面进行二次手术,包括切除输尿管囊肿并重新植入输尿管。

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