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结核分枝杆菌,北京基因型菌株与肺结核的影像学表现无关。

Mycobacterium tuberculosis, Beijing genotype strains not associated with radiological presentation of pulmonary tuberculosis.

作者信息

Borgdorff Martien W, Van Deutekom Henk, De Haas Petra E W, Kremer Kristin, Van Soolingen Dick

机构信息

KNCV Tuberculosis Foundation, The Hague, Netherlands.

出版信息

Tuberculosis (Edinb). 2004;84(5):337-40. doi: 10.1016/j.tube.2003.10.002.

Abstract

Mycobacterium tuberculosis strains of the Beijing genotype have been involved in various outbreaks of multidrug-resistant tuberculosis. Some studies suggest that the infection with the Beijing genotype is associated with a different host immune response. Since this might also lead to a different chest X-ray (CXR) presentation, we compared CXRs of patients with pulmonary tuberculosis, 33 of whom were infected with the Beijing genotype and 76 with other genotypes. No significant differences were detected. We conclude that the Beijing genotype is not associated with a different CXR presentation.

摘要

北京基因型的结核分枝杆菌菌株已引发多起耐多药结核病疫情。一些研究表明,感染北京基因型与不同的宿主免疫反应有关。由于这也可能导致不同的胸部X光(CXR)表现,我们比较了肺结核患者的胸部X光片,其中33例感染了北京基因型,76例感染了其他基因型。未检测到显著差异。我们得出结论,北京基因型与不同的胸部X光表现无关。

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