Elliott Mary E, Drinka Paul J, Krause Peggy, Binkley Neil C, Mahoney Jane E
University of Wisconsin School of Pharmacy, 777 Highland Avenue, Madison, WI 53705, USA.
Maturitas. 2004 Jul 15;48(3):225-33. doi: 10.1016/j.maturitas.2003.11.005.
Twenty-five to thirty percent of hip fractures occur in men, and nursing home residents have a 5-10-fold greater fracture risk than community-dwellers. Osteoporosis prevalence in men in long-term care, however, is poorly defined. Our objectives were to determine the prevalence of osteoporosis, as assessed by peripheral bone mineral density (BMD), in a group of institutionalized veterans, and to determine how many men with low BMD had received a prior diagnosis of osteoporosis.
Subjects were residents in a 740-bed skilled nursing facility (78% men). Male residents (n = 103) competent to give informed consent underwent bilateral calcaneal and forearm BMD by dual-energy X-ray absorptiometry (DXA). Prior osteoporosis documentation was sought in medical records.
Twenty percent of veterans (95% confidence interval (CI) 12-28%) exhibited calcaneal osteoporosis (T-score < -2.5), and 62% (CI 52-72%) were osteoporotic at the forearm. Forearm and calcaneal BMD were correlated (r = 0.678, P < 0.001). BMD of the left and right forearm, and of left and right calcaneus, were highly correlated (r = 0.880, P < 0.001 and r = 0.931, P < 0.001, respectively). Documentation of osteoporosis existed for one of 20 men with calcaneal osteoporosis and four of 59 men with forearm osteoporosis.
Osteoporosis was prevalent but poorly documented in institutionalized veterans. Discordance in T-scores between forearm and heel was similar to that reported in other studies. The broad range of T-scores among subjects suggests that peripheral BMD measurement may be useful for clinical fracture risk stratification. Correlation among skeletal sites indicates that measuring a single site may be practical.
25%至30%的髋部骨折发生在男性身上,疗养院居民的骨折风险比社区居民高5至10倍。然而,长期护理机构中男性骨质疏松症的患病率尚不清楚。我们的目的是通过外周骨密度(BMD)评估,确定一组住院退伍军人中骨质疏松症的患病率,并确定有多少骨密度低的男性此前已被诊断为骨质疏松症。
研究对象为一家拥有740张床位的专业护理机构的居民(78%为男性)。有能力给予知情同意的男性居民(n = 103)通过双能X线吸收法(DXA)进行双侧跟骨和前臂骨密度测量。在病历中查找先前的骨质疏松症记录。
20%的退伍军人(95%置信区间(CI)12 - 28%)表现出跟骨骨质疏松症(T值 < -2.5),62%(CI 52 - 72%)在前臂存在骨质疏松症。前臂和跟骨骨密度呈正相关(r = 0.678,P < 0.001)。左右前臂以及左右跟骨的骨密度高度相关(分别为r = 0.880,P < 0.001和r = 0.931,P < 0.001)。20名跟骨骨质疏松症男性中有1人有骨质疏松症记录,59名前臂骨质疏松症男性中有4人有记录。
骨质疏松症在住院退伍军人中普遍存在,但记录不充分。前臂和足跟T值的不一致与其他研究报道相似。研究对象的T值范围广泛表明,外周骨密度测量可能有助于临床骨折风险分层。骨骼部位之间的相关性表明测量单个部位可能是可行的。