Gutman Benjamin L, Niyogi Krishna K
Department of Plant and Microbial Biology, University of California, Berkeley, California 94720-3102, USA.
Plant Physiol. 2004 Jun;135(2):607-10. doi: 10.1104/pp.104.041491.
A translational biology perspective on Chlamydomonas and Arabidopsis might be expected to focus on those genes, cellular components, or biological processes found first in Chlamydomonas and subsequently studied in Arabidopsis. There are indeed many such examples. There are also examples that flow from Arabidopsis to Chlamydomonas in terms of initial discovery and subsequent study. However, the differences can also be illuminating. In this brief essay, we make a case for the pairing of Chlamydomonas and Arabidopsis as model organisms that bracket a major subset of photosynthetic eukaryotes, the green plants (Mishler, 2000). By analogy with the yeast-mouse dyad, this green pair has tremendous potential as we enter an era of renewed interest in comparative biology.
从转化生物学的角度来看,衣藻和拟南芥可能会侧重于那些首先在衣藻中发现并随后在拟南芥中进行研究的基因、细胞成分或生物学过程。确实有许多这样的例子。在最初发现和后续研究方面,也有从拟南芥流向衣藻的例子。然而,这些差异也可能具有启发性。在这篇短文里,我们提出将衣藻和拟南芥作为模式生物配对的理由,它们涵盖了光合真核生物的一个主要子集——绿色植物(米什勒,2000年)。与酵母 - 小鼠二元组类似,随着我们进入对比较生物学重新产生兴趣的时代,这一绿色组合具有巨大潜力。