Suppr超能文献

老年人自我报告的饮酒情况与跌倒:心血管健康研究的横断面和纵向分析

Self-reported alcohol consumption and falls in older adults: cross-sectional and longitudinal analyses of the cardiovascular health study.

作者信息

Mukamal Kenneth J, Mittleman Murray A, Longstreth W T, Newman Anne B, Fried Linda P, Siscovick David S

机构信息

Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

出版信息

J Am Geriatr Soc. 2004 Jul;52(7):1174-9. doi: 10.1111/j.1532-5415.2004.52318.x.

Abstract

OBJECTIVES

To assess the cross-sectional and longitudinal associations between alcohol consumption and risk of falls in older adults.

DESIGN

Cross-sectional and longitudinal analyses.

SETTING

Four U.S. communities.

PARTICIPANTS

A total of 5,841 older adults enrolled in the Cardiovascular Health Study, an ongoing, population-based, prospective cohort study, participated.

MEASUREMENTS

Self-reported alcohol consumption at baseline, self-reported frequent falls at baseline, and the 4-year risk of falls of participants who denied frequent falls at baseline.

RESULTS

Cross-sectional analysis indicated an apparent inverse association between alcohol consumption and risk of frequent falls (adjusted odds ratio in consumers of 14 or more drinks per week=0.41; 95% confidence interval (CI)=0.14-1.17; P for trend=.06), but longitudinal analysis indicated a similar 4-year risk of falls in abstainers and light to moderate drinkers but a 25% higher risk in consumers of 14 or more drinks per week (95% CI=3-52%; P for trend=.07). Similar results were found in analyses stratified by age, sex, race, and physical activity.

CONCLUSION

Consumption of 14 or more drinks per week is associated with an increased risk of subsequent falls in older adults. Cross-sectional studies may fail to identify this risk of heavier drinking, perhaps because older adults at risk for falls decrease their alcohol use over time or because heavier drinkers at risk for falls tend not to enroll in cohort studies. However, because this study relied upon annual reporting of falls, further prospective studies should be conducted to confirm these findings.

摘要

目的

评估老年人饮酒与跌倒风险之间的横断面和纵向关联。

设计

横断面和纵向分析。

地点

美国四个社区。

参与者

共有5841名参与心血管健康研究的老年人,该研究是一项正在进行的、基于人群的前瞻性队列研究。

测量

基线时自我报告的饮酒情况、基线时自我报告的频繁跌倒情况,以及基线时否认频繁跌倒的参与者的4年跌倒风险。

结果

横断面分析表明饮酒与频繁跌倒风险之间存在明显的负相关(每周饮用14杯或更多酒的消费者的调整优势比=0.41;95%置信区间(CI)=0.14 - 1.17;趋势P值=0.06),但纵向分析表明,戒酒者和轻度至中度饮酒者的4年跌倒风险相似,而每周饮用14杯或更多酒的消费者的风险高25%(95%CI=3 - 52%;趋势P值=0.07)。在按年龄、性别、种族和身体活动分层的分析中发现了类似结果。

结论

每周饮用14杯或更多酒与老年人随后跌倒风险增加有关。横断面研究可能无法识别重度饮酒的这种风险,可能是因为有跌倒风险的老年人随着时间推移减少了饮酒量,或者因为有跌倒风险的重度饮酒者往往不参加队列研究。然而,由于本研究依赖于每年报告跌倒情况,应进行进一步的前瞻性研究以证实这些发现。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验