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老年人的饮酒史与致命伤害

Alcohol-drinking history and fatal injury in older adults.

作者信息

Sorock Gary S, Chen Li-Hui, Gonzalgo Sheila R, Baker Susan P

机构信息

Geriatric Research Services, 312 Central Avenue Glyndon, MD 21071, USA.

出版信息

Alcohol. 2006 Nov;40(3):193-9. doi: 10.1016/j.alcohol.2007.01.002.

Abstract

Although most clinical guidelines for older adults allow for one drink a day in persons without a history of alcoholism, diabetes, or cardiovascular disease, alcohol may contribute to fatal injury in the elderly. Using two national surveys, this case-control study determined the associations between drinking history and fatal injuries from falls, motor vehicle crashes and suicides. We performed a case-control study using 1,735 cases who died of falls, motor vehicle crashes, or suicides selected from the 1993 National Mortality Follow-Back Survey; controls (n=13,381) were a representative sample of the U.S. population from the 1992 National Longitudinal Alcohol Epidemiologic Survey. Cases and controls were restricted to ages 55 years and older. Having 12 or more drinks in the year before death or interview for the controls was used to assess alcohol-drinking history. The unadjusted relative odds for drinkers versus nondrinkers for falls, motor vehicle crashes, and suicides were 1.7, 1.7, and 1.6, respectively. Adjustment for age, gender, marital status, education, and working in the last year did not change these effect estimates, which all excluded the null value. Drinking increased the risk of suicide more for women than for men. Drinking history in older adults is associated about equally with an increased risk of fatal injury from falls, motor vehicle crashes, and suicides.

摘要

尽管大多数针对老年人的临床指南允许无酗酒、糖尿病或心血管疾病史的人每天饮用一杯酒,但酒精可能会导致老年人致命伤害。本病例对照研究利用两项全国性调查,确定饮酒史与跌倒、机动车碰撞及自杀所致致命伤害之间的关联。我们进行了一项病例对照研究,使用了1735例死于跌倒、机动车碰撞或自杀的病例,这些病例选自1993年全国死亡率随访调查;对照组(n = 13381)是来自1992年全国纵向酒精流行病学调查的美国人口代表性样本。病例和对照均限于55岁及以上人群。以对照组在死亡或接受访谈前一年饮用12杯及以上酒来评估饮酒史。跌倒、机动车碰撞及自杀的饮酒者与不饮酒者的未调整相对比值分别为1.7、1.7和1.6。对年龄、性别、婚姻状况、教育程度及上一年工作情况进行调整后,这些效应估计值未改变,且均排除了无效值。饮酒对女性自杀风险的增加作用大于男性。老年人的饮酒史与跌倒、机动车碰撞及自杀所致致命伤害风险增加的关联程度大致相同。

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