慢性疲劳综合征（CFS/ME）的门诊康复治疗。
Outpatient rehabilitative treatment of chronic fatigue syndrome (CFS/ME).
作者信息
Viner R, Gregorowski A, Wine C, Bladen M, Fisher D, Miller M, El Neil S
机构信息
Department of Adolescent Medicine, Great Ormond Street Hospital for Children and University College London Hospitals, London, UK.
出版信息
Arch Dis Child. 2004 Jul;89(7):615-9. doi: 10.1136/adc.2003.035154.
AIMS
To assess the outcome of outpatient multidisciplinary rehabilitative treatment (graded activities/exercise programme, family sessions, and supportive care) compared with supportive care alone for children and adolescents with chronic fatigue syndrome (CFS/ME).
METHODS
Fifty six young people (aged 9-17 years) with CFS/ME by standard criteria were followed up for 3-24 months. All subjects received supportive care. Families additionally opted to either enter the rehabilitation programme (supportive care plus graded activities/exercise programme and family sessions) or have no additional treatment.
RESULTS
Twenty two (39%) subjects had supportive care alone and 26 (46%) entered the programme. Treatment groups were comparable at baseline in terms of age, severity and duration of illness, Wellness score, and school attendance. At end of follow up, those in the programme group had significantly higher Wellness score and school attendance than those having supportive care alone. The programme significantly reduced the overall severity of illness: after the programme, 43% had complete resolution of CFS/ME compared to only 4.5% of those having supportive care alone. The presence of depressed mood and family beliefs about the aetiology of CFS/ME were not significantly associated with outcomes.
CONCLUSIONS
Outpatient rehabilitative treatment offers significant potential to improve the prognosis of CFS/ME in childhood and adolescence.
目的
评估门诊多学科康复治疗（分级活动/锻炼计划、家庭治疗及支持性护理）与单纯支持性护理相比，对慢性疲劳综合征（CFS/ME）儿童及青少年的治疗效果。
方法
采用标准诊断标准确诊的56例9至17岁CFS/ME青少年患者，随访3至24个月。所有受试者均接受支持性护理。部分家庭可选择加入康复计划（支持性护理加分级活动/锻炼计划及家庭治疗）或不接受额外治疗。
结果
22例（39%）受试者仅接受支持性护理，26例（46%）加入康复计划。治疗组在年龄、疾病严重程度及病程、健康评分及上学出勤率方面基线可比。随访结束时，康复计划组的健康评分及上学出勤率显著高于单纯接受支持性护理组。康复计划显著降低了疾病总体严重程度：康复计划后，43%的患者CFS/ME完全缓解，而单纯接受支持性护理的患者仅为4.5%。情绪低落及家庭对CFS/ME病因的看法与治疗效果无显著相关性。
结论
门诊康复治疗对改善儿童及青少年CFS/ME的预后具有显著潜力。
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