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儿科人群慢性疲劳综合征/肌痛性脑脊髓炎的管理:一项范围综述

Management of chronic fatigue syndrome/myalgic encephalomyelitis in a pediatric population: A scoping review.

作者信息

Collard Sarah S, Murphy Jane

机构信息

Faculty of Health and Social Sciences, Bournemouth University, Royal London House, Bournemouth, UK.

出版信息

J Child Health Care. 2020 Sep;24(3):411-431. doi: 10.1177/1367493519864747. Epub 2019 Aug 4.

Abstract

Chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) negatively impacts the quality of life for children with the condition. Although up to 2% of children have CFS/ME, the bulk of research investigates adults with CFS/ME. Using the PRISMA extension for a scoping review and the work of Arksey and O'Malley (2005), a scoping review was conducted of all relevant peer-reviewed research investigating nutrition, exercise, and psychosocial factors within a pediatric population diagnosed with CFS/ME. Key themes found were nutrition and dietary components, exercise therapy, psychosocial factors, and multifaceted treatment. Nutrition was explored on its own as a tool to decrease symptoms; however, there were very few studies found to examine nutritional deficiency or treatment with those under the age of 18. Graded exercise and resistance training improved fatigue severity and symptoms of depression in adolescents with CFS/ME. Research exploring psychosocial factors of CFS/ME presented attributes that could lead to being diagnosed as well as barriers to treatment. The multifaceted treatment undertaken typically consists of graded activities/exercise, cognitive behavioral therapy, nutritional advice, and family sessions. This has shown to increase school attendance and decrease the severity of the fatigue for adolescents. Minimal literature exploring CFS/ME within a prepubescent population presents the need for further research.

摘要

慢性疲劳综合征(CFS)/肌痛性脑脊髓炎(ME)会对患有该病症的儿童的生活质量产生负面影响。尽管高达2%的儿童患有CFS/ME,但大部分研究针对的是患有CFS/ME的成年人。采用PRISMA扩展版进行范围综述,并借鉴阿克西和奥马利(2005年)的研究成果,对所有相关的同行评审研究进行了范围综述,这些研究调查了被诊断患有CFS/ME的儿科人群中的营养、运动和心理社会因素。发现的关键主题包括营养和饮食成分、运动疗法、心理社会因素以及多方面治疗。营养作为减轻症状的一种手段单独进行了探讨;然而,发现很少有研究考察18岁以下人群的营养缺乏或治疗情况。分级运动和阻力训练改善了患有CFS/ME的青少年的疲劳严重程度和抑郁症状。探索CFS/ME心理社会因素的研究呈现了可能导致被诊断的特征以及治疗障碍。通常采用的多方面治疗包括分级活动/运动、认知行为疗法、营养建议和家庭咨询。这已显示可提高青少年的上学出勤率并减轻疲劳的严重程度。在青春期前人群中探索CFS/ME的文献极少,这表明有必要进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70d6/7863118/714b4ae40582/10.1177_1367493519864747-fig1.jpg

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