Greenough A, Alexander J, Burgess S, Bytham J, Chetcuti P A J, Hagan J, Lenney W, Melville S, Shaw N J, Boorman J, Coles S, Turner J, Pang F
Dept of Child Health, King's College Hospital, London SE5 9RS, UK.
Arch Dis Child. 2004 Jul;89(7):673-8. doi: 10.1136/adc.2003.036129.
In prematurely born infants with chronic lung disease (CLD), RSV hospitalisation is associated with increased health service utilisation and costs in the first two years after birth.
To determine whether RSV hospitalisation in the first two years was associated with chronic respiratory morbidity during the preschool years in prematurely born children who had had CLD.
Retrospective review of readmissions, outpatient attendances, and community care in years 2-4 and, at age 5 years, assessment of the children's respiratory status and their health related quality of life. Comparison was made of the results of children who had had at least one hospitalisation in the first two years after birth for RSV infection (RSV group) to those of the rest of the cohort. Participants were 190 of an original cohort of 235 infants with CLD and a median gestational age 27 (range 22-33) weeks.
The 33 children in the RSV group, compared to the rest of the cohort, had a greater duration of hospital stay and more outpatient appointments. The RSV group had required more prescriptions for all treatments and respiratory medications, and more had used an inhaler. The cost of care of the RSV group was higher (median 2630 pounds sterling [4000 Euros, US4800 dollars], range 124-18,091 pounds sterling versus 1360 pounds sterling [2500 Euros, US3000 dollars], range 5-18 929 pounds sterling ) and their health related quality of life was lower.
In prematurely born children who had developed CLD, RSV hospitalisation in the first two years was associated with chronic respiratory morbidity and increased cost of care.
在患有慢性肺病(CLD)的早产婴儿中,呼吸道合胞病毒(RSV)住院与出生后头两年医疗服务利用率增加及成本上升有关。
确定出生后头两年因RSV住院是否与曾患CLD的早产儿童学龄前慢性呼吸道疾病发病率有关。
回顾性分析第2至4年的再入院、门诊就诊和社区护理情况,并在5岁时评估儿童的呼吸状况及其与健康相关的生活质量。将出生后头两年至少因RSV感染住院一次的儿童(RSV组)的结果与队列中其他儿童的结果进行比较。参与者为最初235名CLD婴儿队列中的190名,中位胎龄2