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本文引用的文献

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High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity.高频振荡通气预防早产儿慢性肺病
N Engl J Med. 2002 Aug 29;347(9):633-42. doi: 10.1056/NEJMoa020432.
2
Health care utilisation of infants with chronic lung disease, related to hospitalisation for RSV infection.患有慢性肺病的婴儿因呼吸道合胞病毒(RSV)感染住院的医疗服务利用情况。
Arch Dis Child. 2001 Dec;85(6):463-8. doi: 10.1136/adc.85.6.463.
3
Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7.婴儿期呼吸道合胞病毒细支气管炎是7岁时患哮喘和过敏的重要危险因素。
Am J Respir Crit Care Med. 2000 May;161(5):1501-7. doi: 10.1164/ajrccm.161.5.9906076.
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The Ewing family of tumors. Ewing's sarcoma and primitive neuroectodermal tumors.尤因氏肿瘤家族。尤因肉瘤和原始神经外胚层肿瘤。
Pediatr Clin North Am. 1997 Aug;44(4):991-1004. doi: 10.1016/s0031-3955(05)70541-1.
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Respiratory status and allergy nine to 10 years after acute bronchiolitis.急性细支气管炎发生九至十年后的呼吸状况与过敏情况
Arch Dis Child. 1997 Apr;76(4):315-9. doi: 10.1136/adc.76.4.315.
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Multiattribute utility function for a comprehensive health status classification system. Health Utilities Index Mark 2.用于综合健康状况分类系统的多属性效用函数。健康效用指数Mark 2。
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7
Wheezing, asthma, and pulmonary dysfunction 10 years after infection with respiratory syncytial virus in infancy.婴儿期感染呼吸道合胞病毒10年后出现喘息、哮喘和肺功能障碍。
Br Med J (Clin Res Ed). 1982 Jun 5;284(6330):1665-9. doi: 10.1136/bmj.284.6330.1665.

与呼吸道合胞病毒(RSV)感染住院相关的早产学龄前儿童的医疗保健利用情况。

Health care utilisation of prematurely born, preschool children related to hospitalisation for RSV infection.

作者信息

Greenough A, Alexander J, Burgess S, Bytham J, Chetcuti P A J, Hagan J, Lenney W, Melville S, Shaw N J, Boorman J, Coles S, Turner J, Pang F

机构信息

Dept of Child Health, King's College Hospital, London SE5 9RS, UK.

出版信息

Arch Dis Child. 2004 Jul;89(7):673-8. doi: 10.1136/adc.2003.036129.

DOI:10.1136/adc.2003.036129
PMID:15210503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1720002/
Abstract

BACKGROUND

In prematurely born infants with chronic lung disease (CLD), RSV hospitalisation is associated with increased health service utilisation and costs in the first two years after birth.

AIMS

To determine whether RSV hospitalisation in the first two years was associated with chronic respiratory morbidity during the preschool years in prematurely born children who had had CLD.

METHODS

Retrospective review of readmissions, outpatient attendances, and community care in years 2-4 and, at age 5 years, assessment of the children's respiratory status and their health related quality of life. Comparison was made of the results of children who had had at least one hospitalisation in the first two years after birth for RSV infection (RSV group) to those of the rest of the cohort. Participants were 190 of an original cohort of 235 infants with CLD and a median gestational age 27 (range 22-33) weeks.

RESULTS

The 33 children in the RSV group, compared to the rest of the cohort, had a greater duration of hospital stay and more outpatient appointments. The RSV group had required more prescriptions for all treatments and respiratory medications, and more had used an inhaler. The cost of care of the RSV group was higher (median 2630 pounds sterling [4000 Euros, US4800 dollars], range 124-18,091 pounds sterling versus 1360 pounds sterling [2500 Euros, US3000 dollars], range 5-18 929 pounds sterling ) and their health related quality of life was lower.

CONCLUSION

In prematurely born children who had developed CLD, RSV hospitalisation in the first two years was associated with chronic respiratory morbidity and increased cost of care.

摘要

背景

在患有慢性肺病(CLD)的早产婴儿中,呼吸道合胞病毒(RSV)住院与出生后头两年医疗服务利用率增加及成本上升有关。

目的

确定出生后头两年因RSV住院是否与曾患CLD的早产儿童学龄前慢性呼吸道疾病发病率有关。

方法

回顾性分析第2至4年的再入院、门诊就诊和社区护理情况,并在5岁时评估儿童的呼吸状况及其与健康相关的生活质量。将出生后头两年至少因RSV感染住院一次的儿童(RSV组)的结果与队列中其他儿童的结果进行比较。参与者为最初235名CLD婴儿队列中的190名,中位胎龄2