Research Unit for Neonatal Infectious Diseases and Epidemiology, Medical University of Graz, Graz, Austria.
Department of Paediatrics and Adolescent Medicine, Division of General Paediatrics, Medical University of Graz, Graz, Austria.
Influenza Other Respir Viruses. 2024 Nov;18(11):e70046. doi: 10.1111/irv.70046.
RSV bronchiolitis is a leading cause of hospitalization in infants and young children. We aimed to document the economic burden and epidemiology of RSV over seven seasons in Southern Austria.
All RSV-associated hospitalized (PCR-proven) children ≤ 5 years of age between 1 October 2015 and 30 April 2022 were collected retrospectively. Demographic and epidemiologic data, along with hospitalization costs (direct and indirect), were calculated.
Among 976 children hospitalized due to RSV infection, 87% were healthy term infants, and 79% were < 12 months old. Prematurity (13%) and pre-existing conditions (11%) significantly impacted older children-59% of cases in the 2nd compared with 68% in the 1st year of live. RSV-related hospital costs were approximately €2.0 millions per year (of a total of 60 millions per year). RSV accounted for 19% of hospitalizations due to acute respiratory illness (ARI) in children ≤ 5 years, 37% of all ARI < 6 months, 28% of all ARI < 12 and 6.3% of all-cause hospitalizations < 12 months of age, respectively.
Every 5th hospitalization due to respiratory illness in children ≤ 5 years of age was associated with RSV, representing 7.9% of all hospitalizations and 3.3% of all paediatric hospitalization costs.
呼吸道合胞病毒（RSV）毛细支气管炎是导致婴儿和幼儿住院的主要原因。本研究旨在记录奥地利南部七个流行季节 RSV 的经济负担和流行病学情况。
回顾性收集了 2015 年 10 月 1 日至 2022 年 4 月 30 日期间因呼吸道合胞病毒（PCR 证实）住院的所有≤5 岁的患儿的人口统计学和流行病学数据，以及住院费用（直接和间接）。
在因 RSV 感染住院的 976 名儿童中，87%为健康足月婴儿，79%年龄<12 个月。早产（13%）和基础疾病（11%）显著影响大龄儿童，与 1 岁组相比，2 岁组中分别有 59%和 68%的病例存在上述情况。与 RSV 相关的住院费用约为每年 200 万欧元（每年 6000 万欧元总费用的一部分）。RSV 占≤5 岁儿童因急性呼吸道感染（ARI）住院的 19%，占所有<6 个月 ARI 的 37%，占所有<12 个月 ARI 的 28%，占所有<12 个月儿童住院的 6.3%。
在≤5 岁儿童因呼吸道疾病住院的患儿中，每 5 例中就有 1 例与 RSV 相关，占所有住院的 7.9%，占所有儿科住院费用的 3.3%。
