Li Y W, Polson J W, Dampney R A
Department of Physiology, University of Sydney, N.S.W., Australia.
Brain Res. 1992 Apr 10;577(1):161-4. doi: 10.1016/0006-8993(92)90551-j.
We examined the vasomotor and respiratory effects of angiotensin II microinjection into the rabbit ventrolateral medulla (VLM). Angiotensin II in the rostral and caudal VLM increased and decreased arterial pressure, respectively, but had no effect on phrenic nerve activity. In contrast, L-glutamate injections in the same areas altered both arterial pressure and phrenic nerve activity. The results suggest that angiotensin II may activate specifically vasomotor neurons but not respiratory neurons in the VLM.
我们研究了向家兔延髓腹外侧区（VLM）微量注射血管紧张素II对血管舒缩和呼吸的影响。分别向头端和尾端VLM注射血管紧张素II可使动脉压升高和降低，但对膈神经活动没有影响。相比之下，在相同区域注射L-谷氨酸可改变动脉压和膈神经活动。结果表明，血管紧张素II可能特异性激活VLM中的血管舒缩神经元，而非呼吸神经元。
