Henrichsen Charlotte Neergaard, Delorme Richard, Boucherie Maria, Marelli Dominique, Baud Patrick, Bellivier Franck, Courtet Philippe, Chabane Nadia, Henry Chantal, Leboyer Marion, Malafosse Alain, Antonarakis Stylianos E, Dahoun Sophie
Division de Génétique Médicale, Hôpitaux Universitaires de Genève, 1 rue Michel Servet 1211, Geneva 4, Switzerland.
Am J Med Genet B Neuropsychiatr Genet. 2004 Jul 1;128B(1):80-3. doi: 10.1002/ajmg.b.30037.
Gratacos et al. [2001: Cell 106:367-379] described an interstitial duplication dup(15)q24q26 (DUP25) in patients with anxiety disorders; this duplication was found in approximately 90% of patients and in 7% of controls. In order to determine if DUP25 is present in additional individuals susceptible to panic attacks, we tested 44 patients with anxiety disorders, using probes 251c23 and 216c14 mapping in the 15q24 and 15q26 region. We have not detected any DUP25. Our results suggest that DUP25 is not common in people with anxiety disorders in the population tested here.
