No evidence for DUP25 in patients with panic disorder using a quantitative real-time PCR approach.
作者信息
Schumacher Johannes, Otte Andreas C J, Becker Tim, Sun Yuli, Wienker Thomas F, Wirth Brunhilde, Franke Petra, Abou Jamra Rami, Propping Peter, Deckert Jürgen, Nöthen Markus M, Cichon Sven
机构信息
Institute of Human Genetics, University of Bonn, Wilhelmstrasse 31, 53111 Bonn, Germany.
出版信息
Hum Genet. 2003 Dec;114(1):115-7. doi: 10.1007/s00439-003-1022-5. Epub 2003 Sep 25.
A duplication of chromosome 15q24-q26 (DUP25) has been reported to be associated with anxiety disorders. We tested for the presence of DUP25 in a sample of 50 patients with panic disorder and 50 controls using a quantitative real-time PCR approach. Contrary to the original finding, our results were compatible with the absence of DUP25, and no significant difference could be detected between patients and controls ( P=1.0). Thus, our study does not support the hypothesis of an involvement of DUP25 in panic disorder.
Zotero 插件