Imai Eiko, Kunikata Hiroshi, Udono Tetsuo, Nakagawa Yoichi, Abe Toshiaki, Tamai Makoto
Department of Ophthalmology and Visual Science, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Tohoku J Exp Med. 2004 Jun;203(2):141-4. doi: 10.1620/tjem.203.141.
We report a case of branch retinal artery occlusion (BRAO) in a patient with iron-deficiency anemia. Various ophthalmological and laboratory studies were performed. A 32-year-old man had a sudden decrease of vision in his left eye to counting fingers at 30 cm two days ago. The left fundus showed a cherry-red spot and milky-white edema, except for the upper temporal region of the macula, and an optic disc malformation. Fluorescein angiography revealed leakage from the disc and a slightly delayed filling time in the left eye but an arterial filling defect was not noted. The differential diagnosis in this young patient includes polycythemia, hypercoagulopathy, coagulation abnormalities, trauma, hypertension, and autoimmune diseases such as systemic lupus erythematosus. Laboratory examinations revealed no abnormalities except for iron-deficiency anemia. The patient was treated with stellate ganglion block, hyperbaric oxygen, and ferrous sulfate. His visual acuity never recovered to better than 0.08. He had a coincidental rectal carcinoid and the tumor was excised surgically. No metastasis was observed. BRAO can be a complication of anemic retinopathy and can lead to severe visual loss without early medication.
我们报告一例缺铁性贫血患者发生视网膜分支动脉阻塞(BRAO)的病例。进行了各种眼科和实验室检查。一名32岁男性两天前左眼视力突然下降至30厘米处数指。左眼眼底除黄斑颞上区域外可见樱桃红斑和乳白色水肿,以及视神经盘畸形。荧光素血管造影显示左眼视盘渗漏和充盈时间略有延迟,但未发现动脉充盈缺损。该年轻患者的鉴别诊断包括红细胞增多症、高凝状态、凝血异常、外伤、高血压以及自身免疫性疾病如系统性红斑狼疮。实验室检查除缺铁性贫血外未发现异常。患者接受了星状神经节阻滞、高压氧和硫酸亚铁治疗。其视力从未恢复到优于0.08。他同时患有直肠类癌,肿瘤已手术切除。未观察到转移。BRAO可能是贫血性视网膜病变的并发症,如不及早用药可导致严重视力丧失。