Comba Pietro, Martuzzi Marco, Botti Caterina
Department of Environmental Epidemiology, National Institute of Health, Rome, Italy.
Int J Occup Med Environ Health. 2004;17(1):193-6.
The Precautionary Principle implies the adoption of a set of rules aimed at avoiding possible future harm associated with suspected, but not ascertained, risk factors. Several philosophical, economical and societal questions are implied by precaution-based public health decision making. The purpose of the present paper is to specify the scope of the principle examining the notion of uncertainty involved, and the implication of different approaches to the decision-making process. The Bayesian-utilitarian approach and the approach based on the maximin principle will be considered, and the different meaning of prudence in the two settings will be discussed. In the Bayesian-utilitarian approach the small number of attributable cases will end up in a low average expected value, easily regarded as acceptable in a cost-benefit analysis. In a maximin approach, on the other hand, the issue will be to consider the high etiologic fraction of a rare disease in the highest category of exposure. In the light of the aforementioned cautions in interpretation, the core difference between the two approaches has to do with the choice between averaging knowledge or equitably distributing technological risks.
预防原则意味着采用一套规则,旨在避免与可疑但未确定的风险因素相关的未来可能危害。基于预防的公共卫生决策蕴含着若干哲学、经济和社会问题。本文的目的是明确该原则的范围,审视其中涉及的不确定性概念,以及不同方法对决策过程的影响。将考虑贝叶斯功利主义方法和基于最大最小值原则的方法,并讨论两种情况下审慎的不同含义。在贝叶斯功利主义方法中,少量可归因病例最终会导致较低的平均预期值,在成本效益分析中很容易被视为可接受。另一方面,在最大最小值方法中,问题将是考虑罕见疾病在最高暴露类别中的高病因分数。鉴于上述解释中的注意事项,两种方法的核心差异在于在平均知识或公平分配技术风险之间的选择。