Schneeweiss Sebastian, Dormuth Colin, Grootendorst Paul, Soumerai Stephen B, Maclure Malcolm
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA.
Med Care. 2004 Jul;42(7):653-60. doi: 10.1097/01.mlr.0000129497.10930.a2.
Reference drug pricing (RP) is a cost-sharing strategy commonly used to control drug expenditures. Under RP, a benefit plan fully reimburses medications that are equally or less expensive than the reference price, and requires patients to pay the extra cost of therapeutically equivalent but higher priced drugs. Critics argued that drug plan savings are offset by administrative costs and increased spending on other health services.
We evaluated net healthcare savings in beneficiaries >or=65 years from the perspective of the British Columbia provincial health insurance system after it applied RP to angiotensin-converting enzyme (ACE) inhibitors in 1997.
We estimated savings in new users of antihypertensives after the start of RP plus associated administrative costs and savings from reductions in retail drug prices. Findings were integrated with earlier results on the consequences of RP on expenditures for drugs, physicians, and hospitalizations among all seniors who used ACE inhibitors before the introduction of RP.
During the first year after the implementation of RP, savings for continuous users were CAN dollars 6.0 million. Savings for new users were dollars 0.2 million. Approximately five sixths thereof were achieved by utilization changes and one sixth by cost shifting to patients. There were no savings through drug price changes. Administering RP cost dollars 0.42 million. Overall net savings were estimated to be dollars 5.8 million during the first year after the start of RP. The magnitude of these savings is equal to 6% of all cardiovascular drug expenditures in seniors. After 10 years, approximately 50% of savings will be achieved by new users.
We observed substantial net savings from RP for ACE inhibitors for the provincial health insurance system in British Columbia, although there were generous exemptions from the policy. In other jurisdictions, savings could be higher if drug prices decline after the start of reference pricing.
参考药物定价(RP)是一种常用的成本分担策略,用于控制药物支出。在参考药物定价模式下,医保计划会全额报销价格等于或低于参考价格的药物,而要求患者自行承担治疗等效但价格更高的药物的额外费用。批评者认为,药物计划节省的费用被行政成本和其他医疗服务支出的增加所抵消。
我们从不列颠哥伦比亚省省级医疗保险系统的角度,评估了1997年该系统对血管紧张素转换酶(ACE)抑制剂应用参考药物定价后,65岁及以上受益人的医疗净节省情况。
我们估算了参考药物定价实施后,抗高血压药物新用户的节省费用,以及相关行政成本和零售药品价格降低带来的节省。研究结果与早期关于参考药物定价对所有在参考药物定价实施前使用ACE抑制剂的老年人的药物支出(包括医生诊疗费和住院费)影响的结果相结合。
在参考药物定价实施后的第一年,持续用药者节省了600万加元。新用户节省了20万加元。其中约六分之五的节省是通过用药量的变化实现的,六分之一是通过成本转嫁给患者实现的。药品价格变化未带来节省。实施参考药物定价的行政成本为42万加元。参考药物定价实施后的第一年,总体净节省估计为580万加元。这些节省的幅度相当于老年人所有心血管药物支出的6%。10年后,约50%的节省将由新用户实现。
我们观察到,尽管该政策有大量豁免情况,但不列颠哥伦比亚省省级医疗保险系统在ACE抑制剂的参考药物定价方面实现了可观的净节省。在其他司法管辖区,如果参考定价实施后药品价格下降,节省可能会更高。