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表面增强共振拉曼散射(SERRS)作为一种比荧光检测标记寡核苷酸更灵敏的技术。

SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence.

作者信息

Faulds Karen, Barbagallo Romina P, Keer Jacquie T, Smith W Ewen, Graham Duncan

机构信息

University of Strathclyde, Dept. Pure and Applied Chemistry, 295 Cathedral Street, Glasgow, UKG1 1XL.

出版信息

Analyst. 2004 Jul;129(7):567-8. doi: 10.1039/b406423b. Epub 2004 Jun 3.

Abstract

This communication contains data from a comparison between the detection limits obtained using surface enhanced resonance Raman scattering (SERRS) and fluorescence detection of dye labelled oligonucleotides. The results show that the detection limits for SERRS are generally at least three orders of magnitude lower than those obtained for fluorescence.

摘要

本通讯包含了使用表面增强共振拉曼散射(SERRS)与染料标记寡核苷酸的荧光检测所获得的检测限之间比较的数据。结果表明,SERRS的检测限通常比荧光检测所获得的检测限至少低三个数量级。

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