Goldstein R S
Department of Medicine, University of Toronto, Ontario, Canada.
Clin Chest Med. 1992 Sep;13(3):507-21.
Patients with neuromuscular and chest wall disorders are vulnerable at night when alterations in ventilatory mechanics and control associated with their disease are imposed on the changes in mechanics and control associated with sleep. The physiologic and clinical consequences of these events may be reversed by nocturnal mechanical ventilatory support.
患有神经肌肉和胸壁疾病的患者在夜间较为脆弱,此时与他们疾病相关的通气力学和控制方面的改变叠加在与睡眠相关的力学和控制变化之上。这些情况所导致的生理和临床后果可通过夜间机械通气支持得到逆转。