Warwick James M
Department of Nuclear Medicine, Tygerberg Hospital, Stellenbosch University, Francie van Zijl Drive, 7505 Cape Town, South Africa.
Metab Brain Dis. 2004 Jun;19(1-2):113-23. doi: 10.1023/b:mebr.0000027422.48744.a3.
Single photon emission computed tomography (SPECT) is a technique widely used in nuclear medicine for the imaging of the many organs including the skeleton and heart, as well as for whole body imaging for the detection of tumors. The use of tracers of cerebral perfusion and more recently brain neurotransmitter systems has resulted in the development of a number of applications for brain SPECT in neurology and psychiatry. Indications have been established in cases of dementia, epilepsy, neurovascular disorders, Parkinsonism, and following minor head trauma. It also has the potential to be a valuable research tool for the study of in vivo brain function. In this paper an overview will be given of the principles underlying Brain SPECT, the performance of the procedure, and its applications as a diagnostic modality and research tool.
单光子发射计算机断层扫描（SPECT）是核医学中广泛应用的一种技术，用于包括骨骼和心脏在内的多个器官的成像，以及用于检测肿瘤的全身成像。脑灌注示踪剂以及最近的脑神经递质系统示踪剂的使用，已促成了脑SPECT在神经病学和精神病学中的多种应用的发展。在痴呆、癫痫、神经血管疾病、帕金森病以及轻度头部外伤后等病例中，其适应证已确立。它也有潜力成为研究活体脑功能的有价值的研究工具。本文将概述脑SPECT的基本原理、该检查程序的性能及其作为诊断手段和研究工具的应用。
