Endoh R, Suzuki A, Fujii M, Nakayama K
Department of Electrical & Electronics Engineering, Sophia University, 7-1 Kioicho, Chiyodaku, Tokyo, Japan.
Phys Med Biol. 2004 May 21;49(10):1881-9. doi: 10.1088/0031-9155/49/10/004.
We report a simulation study on diffuse reflective optical computed tomography, in which continuous-wave sources and detectors are placed on the plane surface of a semi-infinite body. We adopted a simple Tikhonov regularization in the inverse problem and demonstrated the feasibility of three-dimensional reconstruction of the absorption coefficient change. The spatial resolution of the reconstructed image was shown to be degrading markedly with the depth. The regularization parameter should be chosen appropriately considering the trade-off between the reconstructed image noise and the spatial resolution. We analysed the dependence of the spatial resolution of the reconstructed image on the regularization parameter and the depth, and also the behaviour of the reconstructed image noise on the regularization parameter and the depth.
我们报告了一项关于漫反射光学计算机断层扫描的模拟研究，其中连续波源和探测器放置在半无限体的平面表面上。我们在反问题中采用了简单的蒂霍诺夫正则化方法，并证明了吸收系数变化的三维重建的可行性。结果表明，重建图像的空间分辨率随着深度的增加而显著下降。应在重建图像噪声和空间分辨率之间进行权衡，适当选择正则化参数。我们分析了重建图像的空间分辨率对正则化参数和深度的依赖性，以及重建图像噪声对正则化参数和深度的行为。
