氟马西尼——治疗手段还是毒素。
Flumazenil--treatment or toxin.
作者信息
Seger Donna L
机构信息
Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA.
出版信息
J Toxicol Clin Toxicol. 2004;42(2):209-16. doi: 10.1081/clt-120030946.
PMID:15214628
Abstract
Flumazenil is frequently administered to the poisoned patient. Seizures may be precipitated and resedation may occur in patients who awakened following flumazenil administration. Seizures may increase morbidity and mortality of the overdose. Benefit:Risk ratio of administering flumazenil should be determined in each overdose patient. Indications for flumazenil are limited.
摘要
氟马西尼常用于中毒患者。使用氟马西尼后苏醒的患者可能会引发癫痫发作并再度出现镇静状态。癫痫发作可能会增加过量用药的发病率和死亡率。在每一位过量用药患者中都应确定使用氟马西尼的利弊比。氟马西尼的适应证有限。
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