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一名霍奇金病患者在接受阿霉素和放疗后怀孕,发生扩张型心肌病:病例报告

Dilated cardiomyopathy in a pregnant woman after doxorubicin and radiotherapy for Hodgkin's disease: a case report.

作者信息

Hadar Amnon, Sheiner Eyal, Press Fernanda, Katz Amos, Katz Miriam

机构信息

Department of Obstetrics and Gynecology A , Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel.

出版信息

J Reprod Med. 2004 May;49(5):401-3.

Abstract

BACKGROUND

Hodgkin's disease occurs frequently in women of reproductive age. Anthracyclines in general and doxorubicin in particular are integral parts of therapy.

CASE

A 24-year-old primigravida had dilated cardiomyopathy diagnosed at 34 weeks'gestation. Three years earlier she had been treated with chest radiation and combination chemotherapy, including doxorubicin, for Hodgkin's disease.

CONCLUSION

The clinician should be aware of this manifestation. Multidisciplinary supervision throughout pregnancy as well as planned timing and mode of delivery are mandatory.

摘要

背景

霍奇金淋巴瘤在育龄女性中频繁发生。蒽环类药物尤其是多柔比星是治疗的重要组成部分。

病例

一名24岁初产妇在妊娠34周时被诊断为扩张型心肌病。三年前,她因霍奇金淋巴瘤接受了胸部放疗和包括多柔比星在内的联合化疗。

结论

临床医生应了解这种表现。孕期全程多学科监护以及计划好分娩时间和方式是必不可少的。

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