Tabriz M S, Riederer K, Baran J, Khatib R
St John Hospital and Medical Center, Detroit, MI, USA.
Clin Microbiol Infect. 2004 Jul;10(7):624-7. doi: 10.1111/j.1469-0691.2004.00893.x.
Guidelines for blood culture (BC) address the appropriate frequency, number and volume, but no guidelines exist for repeating BCs. The pattern of repeated BCs was studied in all patients hospitalised in December 2001 to determine the extent of and reasons for repeating cultures. BC was repeated in 127 (31.6%) of 405 adults with an initial BC during the study period. All patients with available records (n = 96; 75.6%) were included. The average patient age was 62.2 +/- 15.9 years. In total, 295 BC sets (one to four BCs/set) were obtained, comprising 96 initial and 199 repeats (one to nine repeats/patient). Sixty-nine (34.7%) repeats were taken within 24 h, and 89 (44.7%) within 2-4 days. The most common reason (32.2%) was persistent fever. The result of repeated cultures was: no growth (83.4%), same pathogen (9.1%), new pathogen (2.5%) or contamination (5.0%). Thus, BC repeats accounted for one-third of all BCs handled in the laboratory, with little additional yield. Guidelines for repeating BCs may decrease unnecessary testing.
血培养（BC）指南涉及了合适的频率、数量和采血量，但对于重复进行血培养却没有相关指南。对2001年12月住院的所有患者的重复血培养模式进行了研究，以确定重复培养的程度和原因。在研究期间，405名进行了初始血培养的成人中有127名（31.6%）进行了重复血培养。纳入了所有有可用记录的患者（n = 96；75.6%）。患者的平均年龄为62.2±15.9岁。总共获得了295套血培养（每套1至4次血培养），包括96次初始培养和199次重复培养（每位患者1至9次重复培养）。69次（34.7%）重复培养在24小时内进行，89次（44.7%）在2至4天内进行。最常见的原因（32.2%）是持续发热。重复培养的结果为：无生长（83.4%）、相同病原体（9.1%）、新病原体（2.5%）或污染（5.0%）。因此,重复血培养占实验室处理的所有血培养的三分之一，而额外的阳性检出率很低。关于重复血培养的指南可能会减少不必要的检测。
