Zalaudek I, Argenziano G, Leinweber B, Citarella L, Hofmann-Wellenhof R, Malvehy J, Puig S, Pizzichetta M A, Thomas L, Soyer H P, Kerl H
Department of Dermatology, University of Graz, Austria.
Br J Dermatol. 2004 Jun;150(6):1112-6. doi: 10.1111/j.1365-2133.2004.05924.x.
Dermoscopy improves the diagnostic accuracy in pigmented skin lesions, but it is also useful in the evaluation of nonpigmented skin tumours as it allows the recognition of vascular structures that are not visible to the naked eye. Bowen's disease (BD) or squamous cell carcinoma in situ is usually nonpigmented, but may also rarely be pigmented. Objective To describe the dermoscopic features in a series of pigmented and nonpigmented BD.
Dermoscopic images of 21 histopathologically proven BD were evaluated for the presence of various dermoscopic features. Each lesion was photographed using the Dermaphot (Heine Optotechnik, Herrsching, Germany), at 10-fold magnification, and the colour slides were scanned to digital format using a Kodak Photo CD system.
The majority of cases of BD revealed a peculiar dermoscopic pattern characterized by glomerular vessels (90%) and a scaly surface (90%). In addition, in pigmented BD small brown globules regularly packed in a patchy distribution (90%), and structureless grey to brown pigmentation (80%) were observed.
Dermoscopy can be helpful for diagnosing BD because of the presence of repetitive morphological findings such as glomerular vessels and a scaly surface. In pigmented BD, small brown globules and/or homogeneous pigmentation can be seen as well.
皮肤镜可提高色素性皮肤病变的诊断准确性，在评估非色素性皮肤肿瘤时也很有用，因为它能识别肉眼不可见的血管结构。鲍温病（BD）或原位鳞状细胞癌通常无色素沉着，但也可能很少有色素沉着。目的描述一系列色素性和非色素性BD的皮肤镜特征。
对21例经组织病理学证实的BD的皮肤镜图像进行评估，以确定各种皮肤镜特征的存在情况。使用Dermaphot（德国黑林光学技术公司，黑尔兴）以10倍放大倍数拍摄每个病变，并使用柯达Photo CD系统将彩色幻灯片扫描为数字格式。
大多数BD病例显示出一种特殊的皮肤镜模式，其特征为肾小球样血管（90%）和鳞屑表面（90%）。此外，在色素性BD中，观察到小的棕色小球呈斑片状分布（90%），以及无结构的灰色至棕色色素沉着（80%）。
由于存在重复性形态学表现，如肾小球样血管和鳞屑表面，皮肤镜有助于诊断BD。在色素性BD中，也可见小的棕色小球和/或均匀色素沉着。
