Danescu Sorina, Negrutiu Mircea, Focsan Monica, Baican Adrian
Department of Dermatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Nanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, Cluj-Napoca, Romania.
Front Med (Lausanne). 2024 Apr 25;11:1388835. doi: 10.3389/fmed.2024.1388835. eCollection 2024.
Cutaneous squamous cell carcinoma, a type of non-melanoma skin cancer, is a form of keratinocyte carcinoma that stands as one of the most prevalent cancers, exhibiting a rising frequency. This review provides an overview of the latest literature on imaging methods for diagnosing squamous cell carcinoma (SCC) and actinic keratosis (AK). It discusses the diagnostic criteria, advantages, and disadvantages of various techniques such as dermatoscopy, skin ultrasound (US), and reflectance confocal microscopy (RCM), and line-field confocal optical coherence tomography (LC-OCT). These methods offer benefits including non-invasiveness, rapidity, comprehensive lesion imaging, and enhanced sensitivity, but face challenges like high costs and the need for specialized expertise. Despite obstacles, the use of these innovative techniques is expected to increase with ongoing technological advancements, improving diagnosis and treatment planning for keratinocyte carcinomas. Standardizing LC-OCT imaging algorithms for AK, Bowen's disease, and SCC remains an area for further research.
皮肤鳞状细胞癌是一种非黑色素瘤皮肤癌，是角质形成细胞癌的一种形式，是最常见的癌症之一，且发病率呈上升趋势。本综述概述了有关诊断鳞状细胞癌（SCC）和光化性角化病（AK）的成像方法的最新文献。它讨论了各种技术的诊断标准、优缺点，如皮肤镜检查、皮肤超声（US）、反射式共聚焦显微镜（RCM）和线场共聚焦光学相干断层扫描（LC-OCT）。这些方法具有非侵入性、快速、全面的病变成像和更高的灵敏度等优点，但也面临高成本和需要专业知识等挑战。尽管存在障碍，但随着技术的不断进步，预计这些创新技术的使用将会增加，从而改善角质形成细胞癌的诊断和治疗计划。为AK、鲍恩病和SCC标准化LC-OCT成像算法仍是一个有待进一步研究的领域。
