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银屑病中的足部皮肤癣菌感染

Pedal dermatophyte infection in psoriasis.

作者信息

Hamnerius N, Berglund J, Faergemann J

机构信息

Department of Dermatology, Blekinge Hospital, S-371 85 Karlskrona, Sweden.

出版信息

Br J Dermatol. 2004 Jun;150(6):1125-8. doi: 10.1111/j.1365-2133.2004.05959.x.

DOI:10.1111/j.1365-2133.2004.05959.x
PMID:15214898
Abstract

BACKGROUND

Dermatophyte infections have been considered rare in psoriasis. However, there are data indicating that tinea unguium is as common or even more common in psoriasis compared with healthy controls. Tinea unguium is generally a secondary event to tinea pedis infection.

OBJECTIVES

To study the prevalence of tinea pedis and tinea unguium in psoriasis compared with a control group.

METHODS

Consecutive psoriasis outpatients aged 18-64 years attending a department of dermatology were examined. Samples for direct microscopy and culture were taken from the interdigital spaces, soles and toenails. Consecutive patients without signs of psoriasis or atopic dermatitis seeking examination of moles constituted the control group.

RESULTS

In total, 239 patients with psoriasis and 245 control patients were studied. The prevalence of tinea pedis was 8.8%[95% confidence interval (CI) +/- 3.6%] in the psoriasis group and 7.8% (95% CI +/- 3.4%) in the control group. The corresponding figures for prevalence of tinea unguium were 4.6% (95% CI +/- 2.7%) and 2.4% (95% CI +/- 1.9%), respectively. The differences found in the psoriasis vs. the control groups were not statistically significant.

CONCLUSIONS

This study does not support the hypothesis that the prevalence of tinea pedis and tinea unguium in patients with psoriasis differs from that in a normal population.

摘要

背景

皮肤癣菌感染在银屑病中一直被认为较为罕见。然而,有数据表明,与健康对照相比,甲癣在银屑病中同样常见甚至更为常见。甲癣通常是足癣感染的继发事件。

目的

研究银屑病患者中足癣和甲癣的患病率,并与对照组进行比较。

方法

对皮肤科门诊年龄在18至64岁的连续银屑病患者进行检查。从指间、脚底和趾甲处采集样本用于直接显微镜检查和培养。连续的无银屑病或特应性皮炎体征且寻求痣检查的患者构成对照组。

结果

共研究了239例银屑病患者和245例对照患者。银屑病组足癣患病率为8.8%[95%置信区间(CI)±3.6%],对照组为7.8%(95%CI±3.4%)。甲癣患病率的相应数字分别为4.6%(95%CI±2.7%)和2.4%(95%CI±1.9%)。银屑病组与对照组之间的差异无统计学意义。

结论

本研究不支持银屑病患者中足癣和甲癣患病率与正常人群不同的假设。

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