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Microflora of Tafí Cheese: Changes During Manufacture and Maturation.塔菲奶酪的微生物群落：制作和成熟过程中的变化
J Food Prot. 1983 Jun;46(6):518-521. doi: 10.4315/0362-028X-46.6.518.
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Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: kill curves versus MIC.抗感染药物的药代动力学和药效学问题：杀菌曲线与最低抑菌浓度
Antimicrob Agents Chemother. 2004 Feb;48(2):369-77. doi: 10.1128/AAC.48.2.369-377.2004.
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Enhancement of antibiotic activity by sub-lethal concentrations of enterocin CRL35.亚致死浓度的肠球菌素CRL35对抗生素活性的增强作用。
J Antimicrob Chemother. 2004 Feb;53(2):240-6. doi: 10.1093/jac/dkh079. Epub 2004 Jan 16.
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Inhibition of enterocin CRL35 antibiotic activity by mono- and divalent ions.单价和二价离子对肠球菌素CRL35抗生素活性的抑制作用。
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5
Enterocin CRL35 inhibits late stages of HSV-1 and HSV-2 replication in vitro.肠球菌素CRL35在体外抑制单纯疱疹病毒1型和2型复制的后期阶段。
Antiviral Res. 2003 Mar;58(1):17-24. doi: 10.1016/s0166-3542(02)00099-2.
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Biochemical and genetic characterization of mundticin KS, an antilisterial peptide produced by Enterococcus mundtii NFRI 7393.鹑鸡肠球菌NFRI 7393产生的抗李斯特菌肽mundticin KS的生化及遗传特性
Appl Environ Microbiol. 2002 Aug;68(8):3830-40. doi: 10.1128/AEM.68.8.3830-3840.2002.
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Ribosomally synthesized antibacterial peptides in Gram positive bacteria.革兰氏阳性菌中核糖体合成的抗菌肽。
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Bacteriocins: safe, natural antimicrobials for food preservation.细菌素：用于食品保鲜的安全天然抗菌剂。
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9
Analogues of bacteriocins: antimicrobial specificity and interactions of leucocin A with its enantiomer, carnobacteriocin B2, and truncated derivatives.细菌素类似物：抗菌特异性以及亮菌素A与其对映体、肉杆菌素B2和截短衍生物的相互作用
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Preliminary characterization of bacteriocins produced by Enterococcus faecium and Enterococcus faecalis isolated from pig faeces.从猪粪便中分离出的粪肠球菌和屎肠球菌所产细菌素的初步特性分析
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源自NH2末端序列的合成肽增强肠球菌素CRL35的活性。

Enhancement of the enterocin CRL35 activity by a synthetic peptide derived from the NH2-terminal sequence.

作者信息

Saavedra Lucila, Minahk Carlos, de Ruiz Holgado Aída P, Sesma Fernando

机构信息

Centro de Referencia para Lactobacilos (CERELA-CONICET), S.M. de Tucumán (4000), Chacabuco 145, Tucumán, Argentina.

出版信息

Antimicrob Agents Chemother. 2004 Jul;48(7):2778-81. doi: 10.1128/AAC.48.7.2778-2781.2004.

DOI:10.1128/AAC.48.7.2778-2781.2004
PMID:15215149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC434193/
Abstract

The enterocin CRL35 biosynthetic gene cluster was cloned and sequenced. The sequence was revealed to be highly identical to that of the mundticin KS gene cluster (S. Kawamoto, J. Shima, R. Sato, T. Eguchi, S. Ohmomo, J. Shibato, N. Horikoshi, K. Takeshita, and T. Sameshima, Appl. Environ. Microbiol. 68:3830-3840, 2002). Short synthetic peptides were designed based on the bacteriocin sequence and were evaluated in antimicrobial competitive assays. The peptide KYYGNGVSCNKKGCS produced an enhancement of enterocin CRL35 antimicrobial activity in a buffer system.

摘要

克隆并测序了肠球菌素CRL35生物合成基因簇。结果显示该序列与蒙地菌素KS基因簇的序列高度同源（S. 川本、J. 岛、R. 佐藤、T. 江口、S. 大藻藻、J. 柴幡、N. 堀越、K. 竹下和T. ameshima，《应用与环境微生物学》68:3830 - 3840，2002年）。基于该细菌素序列设计了短合成肽，并在抗菌竞争试验中进行了评估。肽KYYGNGVSCNKKGCS在缓冲系统中增强了肠球菌素CRL35的抗菌活性。