Study design questions in treatment of children with acute otitis media.
作者信息
Hoberman Alejandro, Paradise Jack L
出版信息
Antimicrob Agents Chemother. 2004 Jul;48(7):2784; author reply 2785-6. doi: 10.1128/AAC.48.7.2784-2786.2004.
Abstract
摘要
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Antimicrob Agents Chemother. 2004 Jul;48(7):2784; author reply 2785-6. doi: 10.1128/AAC.48.7.2784-2786.2004.
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本文引用的文献
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Rationale for single and high dose treatment regimens with azithromycin.阿奇霉素单剂量和高剂量治疗方案的理论依据。
Pediatr Infect Dis J. 2004 Feb;23(2 Suppl):S102-7. doi: 10.1097/01.inf.0000112523.95762.f5.
2
Open label, multicenter study of gatifloxacin treatment of recurrent otitis media and acute otitis media treatment failure.
Pediatr Infect Dis J. 2003 Nov;22(11):949-56. doi: 10.1097/01.inf.0000095193.42502.d1.
3
Bacteriologic and clinical efficacy of oral gatifloxacin for the treatment of recurrent/nonresponsive acute otitis media: an open label, noncomparative, double tympanocentesis study.口服加替沙星治疗复发性/难治性急性中耳炎的细菌学及临床疗效：一项开放标签、非对照、双鼓膜穿刺研究
Pediatr Infect Dis J. 2003 Nov;22(11):943-9. doi: 10.1097/01.inf.0000095468.89866.14.
4
Correlation between bacteriologic and clinical endpoints in trials of acute otitis media.急性中耳炎试验中细菌学终点与临床终点之间的相关性
Pediatr Infect Dis J. 2003 Oct;22(10):936-7; author reply 937. doi: 10.1097/01.inf.0000092637.66762.c6.
5
High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media.大剂量阿奇霉素与大剂量阿莫西林-克拉维酸治疗复发性或持续性急性中耳炎患儿的疗效比较
Antimicrob Agents Chemother. 2003 Oct;47(10):3179-86. doi: 10.1128/AAC.47.10.3179-3186.2003.
6
Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis.单次剂量阿奇霉素对经鼓膜穿刺术作为基线检查的儿童急性中耳炎的治疗效果。
Antimicrob Agents Chemother. 2003 Aug;47(8):2663-5. doi: 10.1128/AAC.47.8.2663-2665.2003.
7
Flaws in design and conduct of clinical trials in acute otitis media.急性中耳炎临床试验的设计与实施缺陷
Pediatr Infect Dis J. 2002 Oct;21(10):894-902. doi: 10.1097/00006454-200210000-00003.
8
Experimental acute otitis media due to nontypeable Haemophilus influenzae: comparison of high and low azithromycin doses with placebo.由不可分型流感嗜血杆菌引起的实验性急性中耳炎：阿奇霉素高剂量和低剂量与安慰剂的比较。
Antimicrob Agents Chemother. 2002 Jul;46(7):2194-9. doi: 10.1128/AAC.46.7.2194-2199.2002.
9
Bacteriologic and clinical efficacy of high dose amoxicillin/clavulanate in children with acute otitis media.高剂量阿莫西林/克拉维酸治疗儿童急性中耳炎的细菌学及临床疗效
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Noninferiority trials.非劣效性试验。
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