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1
Study design questions in treatment of children with acute otitis media.儿童急性中耳炎治疗中的研究设计问题。
Antimicrob Agents Chemother. 2004 Jul;48(7):2784; author reply 2785-6. doi: 10.1128/AAC.48.7.2784-2786.2004.
2
Study design questions in treatment of children with acute otitis media.儿童急性中耳炎治疗中的研究设计问题。
Antimicrob Agents Chemother. 2004 Jul;48(7):2784-5; author reply 2785-6. doi: 10.1128/AAC.48.7.2784-2786.2004.
3
Effects of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media.阿莫西林/克拉维酸或阿奇霉素对急性中耳炎患儿肺炎链球菌和流感嗜血杆菌鼻咽部携带情况的影响。
Clin Infect Dis. 2000 Oct;31(4):875-80. doi: 10.1086/318160. Epub 2000 Oct 25.
4
Large dosage amoxicillin/clavulanate, compared with azithromycin, for the treatment of bacterial acute otitis media in children.大剂量阿莫西林/克拉维酸与阿奇霉素治疗儿童细菌性急性中耳炎的比较。
Pediatr Infect Dis J. 2005 Jun;24(6):525-32. doi: 10.1097/01.inf.0000164794.50281.1a.
5
Bacterial etiology of acute otitis media and clinical efficacy of amoxicillin-clavulanate versus azithromycin.急性中耳炎的细菌病因及阿莫西林-克拉维酸与阿奇霉素的临床疗效
Int J Pediatr Otorhinolaryngol. 2006 May;70(5):915-23. doi: 10.1016/j.ijporl.2005.10.004. Epub 2005 Nov 15.
6
High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media.大剂量阿奇霉素与大剂量阿莫西林-克拉维酸治疗复发性或持续性急性中耳炎患儿的疗效比较
Antimicrob Agents Chemother. 2003 Oct;47(10):3179-86. doi: 10.1128/AAC.47.10.3179-3186.2003.
7
Role of Streptococcus pneumoniae and Haemophilus influenzae in the development of acute otitis media and otitis media with effusion in a gerbil model.肺炎链球菌和流感嗜血杆菌在沙土鼠模型中急性中耳炎和分泌性中耳炎发病过程中的作用
J Infect Dis. 2000 Feb;181(2):646-52. doi: 10.1086/315237.
8
Prescribing antimicrobial agents for treatment of acute otitis media.
Pediatr Infect Dis J. 1999 Dec;18(12):1141-6. doi: 10.1097/00006454-199912000-00029.
9
Bacteriologic and clinical efficacy of amoxicillin/clavulanate vs. azithromycin in acute otitis media.阿莫西林/克拉维酸与阿奇霉素治疗急性中耳炎的细菌学及临床疗效比较
Pediatr Infect Dis J. 2000 Feb;19(2):95-104. doi: 10.1097/00006454-200002000-00002.
10
A multicenter, open label trial of azithromycin vs. amoxicillin/ clavulanate for the management of acute otitis media in children.一项比较阿奇霉素与阿莫西林/克拉维酸治疗儿童急性中耳炎的多中心开放标签试验。
Pediatr Infect Dis J. 1996 Sep;15(9 Suppl):S15-9. doi: 10.1097/00006454-199609009-00003.

本文引用的文献

1
Rationale for single and high dose treatment regimens with azithromycin.阿奇霉素单剂量和高剂量治疗方案的理论依据。
Pediatr Infect Dis J. 2004 Feb;23(2 Suppl):S102-7. doi: 10.1097/01.inf.0000112523.95762.f5.
2
Open label, multicenter study of gatifloxacin treatment of recurrent otitis media and acute otitis media treatment failure.
Pediatr Infect Dis J. 2003 Nov;22(11):949-56. doi: 10.1097/01.inf.0000095193.42502.d1.
3
Bacteriologic and clinical efficacy of oral gatifloxacin for the treatment of recurrent/nonresponsive acute otitis media: an open label, noncomparative, double tympanocentesis study.口服加替沙星治疗复发性/难治性急性中耳炎的细菌学及临床疗效：一项开放标签、非对照、双鼓膜穿刺研究
Pediatr Infect Dis J. 2003 Nov;22(11):943-9. doi: 10.1097/01.inf.0000095468.89866.14.
4
Correlation between bacteriologic and clinical endpoints in trials of acute otitis media.急性中耳炎试验中细菌学终点与临床终点之间的相关性
Pediatr Infect Dis J. 2003 Oct;22(10):936-7; author reply 937. doi: 10.1097/01.inf.0000092637.66762.c6.
5
High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media.大剂量阿奇霉素与大剂量阿莫西林-克拉维酸治疗复发性或持续性急性中耳炎患儿的疗效比较
Antimicrob Agents Chemother. 2003 Oct;47(10):3179-86. doi: 10.1128/AAC.47.10.3179-3186.2003.
6
Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis.单次剂量阿奇霉素对经鼓膜穿刺术作为基线检查的儿童急性中耳炎的治疗效果。
Antimicrob Agents Chemother. 2003 Aug;47(8):2663-5. doi: 10.1128/AAC.47.8.2663-2665.2003.
7
Flaws in design and conduct of clinical trials in acute otitis media.急性中耳炎临床试验的设计与实施缺陷
Pediatr Infect Dis J. 2002 Oct;21(10):894-902. doi: 10.1097/00006454-200210000-00003.
8
Experimental acute otitis media due to nontypeable Haemophilus influenzae: comparison of high and low azithromycin doses with placebo.由不可分型流感嗜血杆菌引起的实验性急性中耳炎：阿奇霉素高剂量和低剂量与安慰剂的比较。
Antimicrob Agents Chemother. 2002 Jul;46(7):2194-9. doi: 10.1128/AAC.46.7.2194-2199.2002.
9
Bacteriologic and clinical efficacy of high dose amoxicillin/clavulanate in children with acute otitis media.高剂量阿莫西林/克拉维酸治疗儿童急性中耳炎的细菌学及临床疗效
Pediatr Infect Dis J. 2001 Sep;20(9):829-37. doi: 10.1097/00006454-200109000-00002.
10
Noninferiority trials.非劣效性试验。
Curr Control Trials Cardiovasc Med. 2000;1(1):19-21. doi: 10.1186/cvm-1-1-019.

Study design questions in treatment of children with acute otitis media.

作者信息

Hoberman Alejandro, Paradise Jack L

出版信息

Antimicrob Agents Chemother. 2004 Jul;48(7):2784; author reply 2785-6. doi: 10.1128/AAC.48.7.2784-2786.2004.

DOI:10.1128/AAC.48.7.2784-2786.2004
PMID:15215151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC434202/
Abstract
摘要