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BSDD:生物分子片段显示设备——一种基于网络的交互式显示工具。

BSDD: Biomolecules Segment Display Device--a web-based interactive display tool.

作者信息

Selvarani P, Shanthi V, Rajesh C K, Saravanan S, Sekar K

机构信息

Bioinformatics Centre, Indian Institute of Science, Bangalore 560 012, India.

出版信息

Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W645-8. doi: 10.1093/nar/gkh420.

Abstract

An interactive web-based display tool, Biomolecules Segment Display Device (BSDD), has been developed to search for and visualize a user-defined motif or fragment among the protein structures available in the Protein Data Bank (PDB). In addition, the tool works for the structures available in a selected sub-set of non-homologous protein structures (25% and 90% sequence identity). The graphics package RASMOL has been incorporated as an interface to visualize the three-dimensional structure of the user-defined motif. In addition, the software can be used to extract the atomic coordinates of the required fragment and save them to the client system. The atomic coordinates are updated every week from the RCSB-PDB server, and hence the results produced by BSDD are up to date at any given time. The software BSDD is available over the World Wide Web at http://iris.physics.iisc.ernet.in/bsdd or http://144.16.71.2/bsdd.

摘要

已经开发了一种基于网络的交互式显示工具——生物分子片段显示设备(BSDD),用于在蛋白质数据库(PDB)中可用的蛋白质结构中搜索并可视化用户定义的基序或片段。此外,该工具适用于非同源蛋白质结构选定子集中(序列同一性为25%和90%)可用的结构。图形软件包RASMOL已被用作可视化用户定义基序三维结构的接口。此外,该软件可用于提取所需片段的原子坐标并将其保存到客户端系统。原子坐标每周从RCSB-PDB服务器更新一次,因此BSDD产生的结果在任何给定时间都是最新的。软件BSDD可通过万维网在http://iris.physics.iisc.ernet.in/bsdd或http://144.16.71.2/bsdd获取。

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本文引用的文献

1
The Protein Data Bank.蛋白质数据库。
Nucleic Acids Res. 2000 Jan 1;28(1):235-42. doi: 10.1093/nar/28.1.235.
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Three-dimensional structure analysis of PROSITE patterns.PROSITE模式的三维结构分析
J Mol Biol. 1999 Mar 12;286(5):1673-91. doi: 10.1006/jmbi.1999.2581.
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Nucleic Acids Res. 1997 Jan 1;25(1):217-21. doi: 10.1093/nar/25.1.217.
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Enlarged representative set of protein structures.扩大的蛋白质结构代表性集合。
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RASMOL: biomolecular graphics for all.RASMOL:面向所有人的生物分子图形软件。
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