Ananthalakshmi P, Kumar Ch Kiran, Jeyasimhan M, Sumathi K, Sekar K
Bioinformatics Centre, Indian Institute of Science, Bangalore 560 012, India.
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W85-8. doi: 10.1093/nar/gki353.
FF (Fragment Finder) is a web-based interactive search engine developed to retrieve the user-desired similar 3D structural fragments from the selected subset of 25 or 90% non-homologous protein chains. The search is based on the comparison of the main chain backbone conformational angles (phi and ). Additionally, the queried motifs can be superimposed to find out how similar the structural fragments are, so that the information can be effectively used in molecular modeling. The engine has facilities to view the resultant superposed or individual 3D structure(s) on the client machine. The proposed web server is made freely accessible at the following URL: http://cluster.physics.iisc.ernet.in/ff/ or http://144.16.71.148/ff/.
FF(片段查找器)是一个基于网络的交互式搜索引擎,旨在从25%或90%的非同源蛋白质链的选定子集中检索用户所需的相似3D结构片段。该搜索基于主链骨架构象角(φ和ψ)的比较。此外,查询的基序可以进行叠加,以找出结构片段的相似程度,从而使这些信息能够有效地用于分子建模。该引擎具备在客户端机器上查看所得叠加或单个3D结构的功能。所提议的网络服务器可通过以下网址免费访问:http://cluster.physics.iisc.ernet.in/ff/ 或 http://144.16.71.148/ff/ 。