Muthupillai Raja, Flamm Scott D, Wilson James M, Pettigrew Roderic I, Dixon W Thomas
Philips Medical Systems, Cleveland, Ohio, USA.
Radiology. 2004 Aug;232(2):606-10. doi: 10.1148/radiol.2322030334. Epub 2004 Jun 23.
Acute myocardial injury was evaluated in 21 patients by using a contrast material-enhanced T1rho-weighted cine turbo field-echo magnetic resonance (MR) imaging sequence and a delayed-enhancement sequence. In 12 of 21 patients, conventional T1-weighted contrast-enhanced cine turbo field-echo MR images were also collected for direct comparison with T1rho-weighted images. Delayed-enhancement technique distinctly characterized irreversible injury (percentage enhancement, 588% +/- 344). With T1rho weighting, percentage enhancement of irreversibly injured myocardium was 68% +/- 41, compared with 23% +/- 24 without T1rho weighting (P <.006). The addition of T1rho weighting to contrast-enhanced cine turbo field-echo MR sequences may offer a new contrast enhancement mechanism for characterization of acutely infarcted myocardium.
采用对比剂增强的T1rho加权电影快速场回波磁共振（MR）成像序列和延迟增强序列对21例患者进行急性心肌损伤评估。21例患者中的12例还采集了传统T1加权对比增强电影快速场回波MR图像，以便与T1rho加权图像进行直接比较。延迟增强技术能清晰地识别不可逆损伤（增强百分比，588%±344）。采用T1rho加权时，不可逆损伤心肌的增强百分比为68%±41，而未采用T1rho加权时为23%±24（P<.006）。在对比增强电影快速场回波MR序列中加入T1rho加权，可能为急性梗死心肌的特征化提供一种新的对比增强机制。
